Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6J14_RS10435 Genome accession   NZ_CP068057
Coordinates   2090169..2091494 (+) Length   441 a.a.
NCBI ID   WP_003052142.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2085169..2096494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS10410 (I6J14_10410) - 2085848..2086489 (+) 642 WP_003052152.1 response regulator transcription factor -
  I6J14_RS10415 (I6J14_10415) - 2086526..2087926 (+) 1401 WP_115253070.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6J14_RS10420 (I6J14_10420) - 2087926..2088285 (+) 360 WP_003052148.1 S1 RNA-binding domain-containing protein -
  I6J14_RS10425 (I6J14_10425) cysK 2088436..2089371 (-) 936 WP_003052146.1 cysteine synthase A -
  I6J14_RS10430 (I6J14_10430) - 2089475..2090113 (-) 639 WP_003052144.1 YigZ family protein -
  I6J14_RS10435 (I6J14_10435) comFA/cflA 2090169..2091494 (+) 1326 WP_003052142.1 DEAD/DEAH box helicase Machinery gene
  I6J14_RS11130 (I6J14_10440) - 2091466..2092131 (+) 666 WP_115253069.1 ComF family protein -
  I6J14_RS10445 (I6J14_10445) raiA 2092211..2092759 (+) 549 WP_003052138.1 ribosome-associated translation inhibitor RaiA -
  I6J14_RS10450 (I6J14_10450) - 2092714..2093651 (-) 938 Protein_2022 IS30 family transposase -
  I6J14_RS10455 (I6J14_10455) - 2093861..2094208 (+) 348 WP_003052134.1 hypothetical protein -
  I6J14_RS10460 (I6J14_10460) - 2094213..2094401 (+) 189 WP_003052131.1 helix-turn-helix transcriptional regulator -
  I6J14_RS10465 (I6J14_10465) - 2094414..2094809 (+) 396 WP_115253068.1 ATP-binding cassette domain-containing protein -
  I6J14_RS10470 (I6J14_10470) - 2094831..2095109 (+) 279 WP_115253067.1 hypothetical protein -
  I6J14_RS10475 (I6J14_10475) - 2095120..2095470 (+) 351 WP_115253066.1 hypothetical protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49359.45 Da        Isoelectric Point: 9.6283

>NTDB_id=526763 I6J14_RS10435 WP_003052142.1 2090169..2091494(+) (comFA/cflA) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVIIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYASQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDDFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYSNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=526763 I6J14_RS10435 WP_003052142.1 2090169..2091494(+) (comFA/cflA) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGGAAGGTATTGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAATCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGCGGCACTTACTACTGTCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACACCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGTGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCTAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGAGTTACTCTTTTACACGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCATCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAATTAGAGAAGTTGACATTAGCTAGACGATTTCATGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGCCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAGCAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGACTT
TCGTCAAGGAAAGAAAGGCATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGTGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTCGGGAGATCTATCGAAAGG
CCAACAGGAAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTCGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(99-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae D39

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae R6

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae TIGR4

53.081

95.692

0.508
  comFA/cflA Streptococcus mitis NCTC 12261

51.628

97.506

0.503
  comFA/cflA Streptococcus mitis SK321

51.765

96.372

0.499
  comFA Lactococcus lactis subsp. cremoris KW2

45.366

92.971

0.422
  comFA Latilactobacillus sakei subsp. sakei 23K

37.355

97.732

0.365