Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DMB75_RS04370 Genome accession   NZ_CP068031
Coordinates   924316..924945 (+) Length   209 a.a.
NCBI ID   WP_130548292.1    Uniprot ID   -
Organism   Staphylococcus saccharolyticus strain DVP5-16-4677     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 919316..929945
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DMB75_RS04340 (DMB75_004335) isaB 919500..920051 (+) 552 WP_130548287.1 immunodominant staphylococcal antigen IsaB family protein -
  DMB75_RS04345 (DMB75_004340) - 920128..921117 (-) 990 WP_130548288.1 FUSC family protein -
  DMB75_RS04350 (DMB75_004345) map 921294..922049 (+) 756 WP_130548289.1 type I methionyl aminopeptidase -
  DMB75_RS04355 (DMB75_004350) - 922180..922567 (+) 388 Protein_888 hypothetical protein -
  DMB75_RS04360 (DMB75_004355) liaF 922582..923283 (+) 702 WP_130548290.1 cell wall-active antibiotics response protein LiaF -
  DMB75_RS04365 (DMB75_004360) vraS 923280..924326 (+) 1047 WP_130548291.1 sensor histidine kinase Regulator
  DMB75_RS04370 (DMB75_004365) vraR 924316..924945 (+) 630 WP_130548292.1 two-component system response regulator VraR Regulator
  DMB75_RS04375 (DMB75_004370) - 925003..926256 (-) 1254 WP_130548293.1 YihY/virulence factor BrkB family protein -
  DMB75_RS04380 (DMB75_004375) - 926613..926897 (-) 285 WP_130548294.1 YtxH domain-containing protein -
  DMB75_RS04385 (DMB75_004380) - 926904..927368 (-) 465 WP_130548295.1 low molecular weight protein-tyrosine-phosphatase -
  DMB75_RS04390 (DMB75_004385) - 927509..927715 (+) 207 WP_130548296.1 DUF1128 family protein -
  DMB75_RS04395 (DMB75_004390) - 927727..928967 (+) 1241 Protein_896 aminopeptidase -
  DMB75_RS04400 (DMB75_004395) - 929053..929583 (+) 531 WP_130548316.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23615.26 Da        Isoelectric Point: 4.9049

>NTDB_id=526397 DMB75_RS04370 WP_130548292.1 924316..924945(+) (vraR) [Staphylococcus saccharolyticus strain DVP5-16-4677]
MEIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAIEKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYIFKTTSASDIADAVRKTSQGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=526397 DMB75_RS04370 WP_130548292.1 924316..924945(+) (vraR) [Staphylococcus saccharolyticus strain DVP5-16-4677]
GTGGAGATTAAAGTTTTATTTGTAGATGATCATGAAATGGTCAGAATTGGTATTTCTAGTTATCTTTCAACTCAACCAGA
TATTGAGGTTGTAGGAGAGGGGGCTTCAGGTAAAGAAGCAATTGAGAAAGCTCATGAGTTGAAACCAGATTTAATTTTAA
TGGATTTACTTATGGAAGATATGGATGGTGTAGAGGCAACTACGCAAATTAAAAAGGATTTACCGCATATTAAAGTGGTT
ATGCTAACAAGTTTTATTGAAGATAAAGAAGTATACCGTGCCCTTGATGCAGGTGTAGATAGCTACATTTTTAAAACAAC
AAGTGCAAGTGATATTGCTGATGCTGTTCGTAAAACTTCGCAAGGAGAATCAGTTTTTGAACCTGAAGTTTTAGTGAAAA
TGCGTAATCGTATGAAAAAACGTGCAGAATTATATGAAATGCTTACAGAACGTGAAATGGAAATATTGCTACTCATCGCA
AAAGGATACTCTAATCAAGAAATAGCAAGTGCATCACACATCACAATTAAAACAGTAAAAACACACGTAAGTAATATTTT
AAGTAAATTAGAGGTCCAAGATAGAACACAAGCAGTGATTTATGCTTTTCAACATAATCTTATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

96.172

100

0.962
  degU Bacillus subtilis subsp. subtilis str. 168

34.667

100

0.373