Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   JJN14_RS08540 Genome accession   NZ_CP067992
Coordinates   1723904..1724593 (-) Length   229 a.a.
NCBI ID   WP_050283620.1    Uniprot ID   A0A1E9GD25
Organism   Streptococcus mitis strain S022-V7-A3     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1718904..1729593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS08520 (JJN14_08520) mvaD 1719714..1720667 (-) 954 WP_201058421.1 diphosphomevalonate decarboxylase -
  JJN14_RS08525 (JJN14_08525) mvk 1720649..1721527 (-) 879 WP_201058422.1 mevalonate kinase -
  JJN14_RS08530 (JJN14_08530) cbpC 1721756..1722775 (-) 1020 WP_201058423.1 choline-binding protein CbpC -
  JJN14_RS08535 (JJN14_08535) - 1722793..1723803 (-) 1011 WP_201058424.1 N-acetylmuramoyl-L-alanine amidase family protein -
  JJN14_RS08540 (JJN14_08540) covR 1723904..1724593 (-) 690 WP_050283620.1 response regulator transcription factor Regulator
  JJN14_RS08545 (JJN14_08545) gndA 1724605..1726029 (-) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  JJN14_RS08550 (JJN14_08550) mapZ 1726105..1727487 (-) 1383 WP_201058425.1 cell division site-positioning protein MapZ -
  JJN14_RS08555 (JJN14_08555) - 1727500..1728657 (-) 1158 WP_201058426.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  JJN14_RS08565 (JJN14_08565) gpsB 1729144..1729473 (-) 330 WP_000146534.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26766.86 Da        Isoelectric Point: 7.4648

>NTDB_id=526171 JJN14_RS08540 WP_050283620.1 1723904..1724593(-) (covR) [Streptococcus mitis strain S022-V7-A3]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=526171 JJN14_RS08540 WP_050283620.1 1723904..1724593(-) (covR) [Streptococcus mitis strain S022-V7-A3]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCATCTGGGGGATATGACAGCCCAGGATTTTGCAGACAAACTGAGTCGGACTAAGCCAGCCTCAGTCATCATGGTCTTG
GACCATCGTGAAGAATTGCAAGATCAGATTGAGACAATCCAACGCTTTGCCGTTTCGTACATCTATAAGCCAGTTATTAT
TGATAATTTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACATTGTAGTCAGATGAAGGTTC
CAACGTCTTATCGCAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACTCGT
CGTGAGTATGACCTCTTGGCTACTCTTATGGGAAGCAAGAAAGTTCTGACTCGTGAACAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACCAATATCGTGGATGTCTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTCGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E9GD25

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463