Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   JJN14_RS01330 Genome accession   NZ_CP067992
Coordinates   274635..275459 (+) Length   274 a.a.
NCBI ID   WP_042750033.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 269635..280459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS01295 (JJN14_01295) asnA 269726..270718 (+) 993 WP_201058707.1 aspartate--ammonia ligase -
  JJN14_RS01300 (JJN14_01300) rsmD 270783..271322 (+) 540 WP_049551837.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  JJN14_RS01305 (JJN14_01305) coaD 271312..271800 (+) 489 WP_201058708.1 pantetheine-phosphate adenylyltransferase -
  JJN14_RS01310 (JJN14_01310) sepM 271784..272821 (+) 1038 WP_033687316.1 SepM family pheromone-processing serine protease Regulator
  JJN14_RS01315 (JJN14_01315) - 272878..273108 (+) 231 WP_063612229.1 DUF1146 family protein -
  JJN14_RS01320 (JJN14_01320) murA 273132..274415 (+) 1284 WP_201058709.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  JJN14_RS01325 (JJN14_01325) - 274408..274596 (+) 189 WP_004241151.1 DNA-directed RNA polymerase subunit beta -
  JJN14_RS01330 (JJN14_01330) endA 274635..275459 (+) 825 WP_042750033.1 DNA-entry nuclease EndA Machinery gene
  JJN14_RS01335 (JJN14_01335) - 275615..276946 (+) 1332 WP_201058710.1 hemolysin family protein -
  JJN14_RS01345 (JJN14_01345) amiA3 277477..279465 (+) 1989 WP_000749582.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29866.48 Da        Isoelectric Point: 9.8711

>NTDB_id=526136 JJN14_RS01330 WP_042750033.1 274635..275459(+) (endA) [Streptococcus mitis strain S022-V7-A3]
MDKKTRQTLIGLLVLLLLSAGSYYIKQMQSTANSPKTKVSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESMVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=526136 JJN14_RS01330 WP_042750033.1 274635..275459(+) (endA) [Streptococcus mitis strain S022-V7-A3]
ATGGATAAAAAAACAAGACAGACACTGATCGGACTGCTAGTGTTATTGCTTTTATCTGCGGGAAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACAAAGGTTAGTCAGAAAAAACAAGCTTCTGAAGCTCCTAGTCAAGCATTGG
CAGAAAGTGTCTTAACAGACGCAGTCAAAAGCCAAATAAAAGGGAGTCTTGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGATAATAAAACAAAGACAGTGGGCAAGGA
AACAGTGCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCTACTCGCCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CGACTTCATGGACTCCTCCAGGCTGGCATCAGGTTAAGAATCTAAAGGGTACTTATACCCATGCGGTCGATAGAGGTCAC
TTGTTAGGCTATGCCTTAATCGGTGGCTTGGATGGTTTTGATGCCTCGACAAGCAATCCTAAAAACATTGCTGTTCAAAC
AGCCTGGGCAAATCAGGCACAGGCTGAAGATTCGACTGGTCAAAACTACTATGAAAGTATGGTACGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTATTACGCTTCAAACGAGGACTTAGTTCCTTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGACGGAGAATTGGAATTTAATGTCCTAGTTCCCAATGTTCAAAAAGGGCTTCAACTGGATTACCGAAC
TGGAGAAGTAACGGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

95.985

100

0.96
  endA Streptococcus pneumoniae D39

95.985

100

0.96
  endA Streptococcus pneumoniae R6

95.985

100

0.96
  endA Streptococcus pneumoniae TIGR4

95.985

100

0.96