Detailed information NTG0524944

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: C9Q_RS03680
• Genome accession: NZ_CP067090
• Coordinates: 707106..708335 (+)
• Length: 409 a.a.
• NCBI ID: WP_002984948.1
• Uniprot ID: A0A4U7GJW1
• Organism: Streptococcus pyogenes MGAS10870
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 702106..713335

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9Q_RS03655 (C9Q_03640)	-	702722..703999 (-)	1278	WP_002984963.1	hydroxymethylglutaryl-CoA reductase, degradative	-
C9Q_RS03660 (C9Q_03645)	-	703986..705161 (-)	1176	WP_011054378.1	hydroxymethylglutaryl-CoA synthase	-
C9Q_RS03665 (C9Q_03650)	-	705370..706209 (+)	840	WP_010922172.1	thymidylate synthase	-
C9Q_RS03670 (C9Q_03655)	-	706289..706786 (+)	498	WP_002984955.1	dihydrofolate reductase	-
C9Q_RS03675 (C9Q_03660)	-	706806..706976 (+)	171	WP_002984950.1	hypothetical protein	-
C9Q_RS03680 (C9Q_03665)	clpX	707106..708335 (+)	1230	WP_002984948.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
C9Q_RS03685 (C9Q_03670)	yihA	708345..708944 (+)	600	WP_011054379.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
C9Q_RS03690 (C9Q_03675)	-	709092..709838 (+)	747	WP_011054380.1	hypothetical protein	-
C9Q_RS03695 (C9Q_03680)	-	709891..711990 (-)	2100	WP_010922175.1	ATP-dependent Clp protease ATP-binding subunit	-
C9Q_RS03700 (C9Q_03685)	rpiA	712370..713053 (+)	684	WP_010922176.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44991.44 Da
• Isoelectric Point: 4.5775

>NTDB_id=524944 C9Q_RS03680 WP_002984948.1 707106..708335(+) (clpX) [Streptococcus pyogenes MGAS10870]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=524944 C9Q_RS03680 WP_002984948.1 707106..708335(+) (clpX) [Streptococcus pyogenes MGAS10870]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATCGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGCTTGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

3D structure

• AlphaFold DB: A0A4U7GJW1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575