Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   T15_RS00370 Genome accession   NC_022665
Coordinates   60230..62167 (+) Length   645 a.a.
NCBI ID   WP_023369033.1    Uniprot ID   -
Organism   Streptococcus suis T15     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 55230..67167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  T15_RS00350 - 56101..57039 (-) 939 Protein_48 IS4 family transposase -
  T15_RS00355 (T15_0054) - 57179..58399 (+) 1221 WP_023369028.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  T15_RS00365 (T15_0056) - 58589..60112 (+) 1524 WP_023369029.1 Heme/copper-type cytochrome/quinol oxidase subunit 1 -
  T15_RS00370 (T15_0058) hexB 60230..62167 (+) 1938 WP_023369033.1 DNA mismatch repair endonuclease MutL Machinery gene
  T15_RS00375 (T15_0059) ruvA 62206..62796 (+) 591 WP_023369035.1 Holliday junction branch migration protein RuvA Machinery gene
  T15_RS00385 (T15_0060) - 63426..63986 (+) 561 WP_023369037.1 DNA-3-methyladenine glycosylase I -
  T15_RS00390 (T15_0061) - 64060..64470 (+) 411 WP_023369039.1 helix-turn-helix transcriptional regulator -
  T15_RS11200 (T15_0062) - 64443..65108 (+) 666 WP_023369041.1 CPBP family intramembrane glutamic endopeptidase -
  T15_RS00400 (T15_0063) cinA 65253..66434 (+) 1182 WP_023369043.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 73011.25 Da        Isoelectric Point: 5.1164

>NTDB_id=52483 T15_RS00370 WP_023369033.1 60230..62167(+) (hexB) [Streptococcus suis T15]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSQMVIETATANYSHGLRLEAKGGDIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFVLVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSVQQLLVPYIFEFPQNDALDLVHKMAALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=52483 T15_RS00370 WP_023369033.1 60230..62167(+) (hexB) [Streptococcus suis T15]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATCACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCAGATGGTTATTGAGACTGCAACAGCAAATTATTCGCATGGTCTACGATTAGAGGCCAAAGGTGGTGATATCGAGAAAG
AGGAGCCAGTTAGTCGTCCGGTTGGCACACAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCCTT
TGTCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGTTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCACTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCGCAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGTTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGCTGCCCTTCGTCAAGTAGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCGATCAAGGCCAATCA
TGCTCTGGATGATTACTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGCC
GCCCAGTCTTAGTGCATTTCAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-136)

MutL C terminal dimerisation domain (MutL_C)

(447-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.615

100

0.732

Multiple sequence alignment