Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   JHX98_RS01610 Genome accession   NZ_CP067010
Coordinates   295447..296517 (+) Length   356 a.a.
NCBI ID   WP_010921893.1    Uniprot ID   A0A4U9C068
Organism   Streptococcus pyogenes strain iGAS376     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 290447..301517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JHX98_RS01595 (JHX98_01595) amiA 290978..292945 (+) 1968 WP_076640708.1 peptide ABC transporter substrate-binding protein Regulator
  JHX98_RS01600 (JHX98_01600) amiC 293010..294512 (+) 1503 WP_011017334.1 ABC transporter permease Regulator
  JHX98_RS01605 (JHX98_01605) amiD 294512..295438 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  JHX98_RS01610 (JHX98_01610) amiE 295447..296517 (+) 1071 WP_010921893.1 ABC transporter ATP-binding protein Regulator
  JHX98_RS01615 (JHX98_01615) amiF 296510..297433 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  JHX98_RS01625 (JHX98_01625) - 297581..297760 (-) 180 WP_111695866.1 transposase -
  JHX98_RS09590 - 298058..299070 (-) 1013 Protein_277 IS3 family transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39703.77 Da        Isoelectric Point: 5.6707

>NTDB_id=524327 JHX98_RS01610 WP_010921893.1 295447..296517(+) (amiE) [Streptococcus pyogenes strain iGAS376]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=524327 JHX98_RS01610 WP_010921893.1 295447..296517(+) (amiE) [Streptococcus pyogenes strain iGAS376]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATTGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9C068

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537