Detailed information NTG0522166

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JGY90_RS04885
• Genome accession: NZ_CP066726
• Coordinates: 1041220..1042263 (+)
• Length: 347 a.a.
• NCBI ID: WP_042362410.1
• Uniprot ID: A0A5R9B245
• Organism: Staphylococcus xylosus strain TMW 2.1324
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1036220..1047263

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JGY90_RS04860 (JGY90_04830)	-	1037174..1037896 (+)	723	WP_042362406.1	type 1 glutamine amidotransferase	-
JGY90_RS04865 (JGY90_04835)	-	1038099..1039085 (-)	987	WP_042362407.1	aromatic acid exporter family protein	-
JGY90_RS04870 (JGY90_04840)	map	1039262..1040014 (+)	753	WP_039069016.1	type I methionyl aminopeptidase	-
JGY90_RS04875 (JGY90_04845)	-	1040119..1040505 (+)	387	WP_042362408.1	hypothetical protein	-
JGY90_RS04880 (JGY90_04850)	liaF	1040522..1041223 (+)	702	WP_042362409.1	cell wall-active antibiotics response protein LiaF	-
JGY90_RS04885 (JGY90_04855)	vraS	1041220..1042263 (+)	1044	WP_042362410.1	sensor histidine kinase	Regulator
JGY90_RS04890 (JGY90_04860)	vraR	1042253..1042882 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
JGY90_RS04895 (JGY90_04865)	-	1043151..1044296 (-)	1146	WP_042362411.1	YihY/virulence factor BrkB family protein	-
JGY90_RS04900 (JGY90_04870)	-	1044652..1044936 (-)	285	WP_042362412.1	hypothetical protein	-
JGY90_RS04905 (JGY90_04875)	-	1044943..1045407 (-)	465	WP_029378983.1	low molecular weight protein-tyrosine-phosphatase	-
JGY90_RS04910 (JGY90_04880)	-	1045542..1045745 (+)	204	WP_017723498.1	DUF1128 family protein	-
JGY90_RS04915 (JGY90_04885)	-	1045763..1047001 (+)	1239	WP_069794719.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40037.55 Da
• Isoelectric Point: 6.4215

>NTDB_id=522166 JGY90_RS04885 WP_042362410.1 1041220..1042263(+) (vraS) [Staphylococcus xylosus strain TMW 2.1324]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNVMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=522166 JGY90_RS04885 WP_042362410.1 1041220..1042263(+) (vraS) [Staphylococcus xylosus strain TMW 2.1324]
ATGAATCACTACATTAGAGCAATAGGTTCGATGTTGATATTAGTTTATAGTACATTTTTTGCTATATTTTTTATTGATAA
AGTATTTGTTAACGTAATGTACTTTCAAGGTATGTTTTATACCCAAATATTTGGTATACCCGTCTTATTATTTTTAAATT
TAATGGTTATTTTGCTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAACAAAATCATTGGTTAAAAGAC
CAAATAGAAAGATCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACTAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGCTAGCACGTGAATTACATGATTCAGTGAGT
CAGCAGTTGTTCGCAGCTAGCATGATGTTATCAGCAATAAAAGAAACAAAATTAGAGGCACCACTAGATCAGCAAATTCC
GGTACTAGAGAAAATGATTCAAGATTCTCAGCTAGAAATGAGAGCTTTATTACTACATTTAAGACCTATAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGACTTAGTTGTAGATCTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCTATATCGAATACATTAAGGCA
TTCAAAAGGAACAAAAGTAACTATAGAGTTATTTAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTTGATGATAAAGTAGAACAAAGTTATGGCTTAAAAAATATGCGTGAGCGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCACTACCTGATGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A5R9B245

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.473	100	0.885