Detailed information NTG0052170

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: LPV_RS07620
• Genome accession: NC_018140
• Coordinates: 1682364..1683227 (+)
• Length: 287 a.a.
• NCBI ID: WP_014843848.1
• Uniprot ID: I7HUK3
• Organism: Legionella pneumophila subsp. pneumophila
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1677364..1688227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPV_RS07600 (LPV_1652)	-	1677857..1678183 (-)	327	WP_011213802.1	DUF1820 family protein	-
LPV_RS07605 (LPV_1653)	-	1678366..1679109 (-)	744	WP_014843846.1	methyltransferase domain-containing protein	-
LPV_RS07610 (LPV_1654)	pilB	1679368..1681092 (+)	1725	WP_014843847.1	type IV-A pilus assembly ATPase PilB	Machinery gene
LPV_RS07615 (LPV_1655)	pilC	1681098..1682318 (+)	1221	WP_011946524.1	type II secretion system F family protein	Machinery gene
LPV_RS07620 (LPV_1656)	pilD	1682364..1683227 (+)	864	WP_014843848.1	prepilin peptidase	Machinery gene
LPV_RS07625 (LPV_1657)	-	1683241..1684446 (-)	1206	WP_014843849.1	cyclic nucleotide-binding domain-containing protein	-
LPV_RS07630 (LPV_1658)	-	1684554..1685147 (-)	594	WP_011213808.1	hypothetical protein	-
LPV_RS07635 (LPV_1659)	-	1685163..1685618 (-)	456	WP_011213809.1	hypothetical protein	-
LPV_RS07640 (LPV_1660)	-	1685752..1686567 (+)	816	WP_010947257.1	pyruvate, water dikinase regulatory protein	-
LPV_RS07645 (LPV_1661)	-	1686687..1688135 (-)	1449	WP_014843850.1	bifunctional 2-methylcitrate dehydratase/aconitate hydratase	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 32774.37 Da
• Isoelectric Point: 7.8327

>NTDB_id=52170 LPV_RS07620 WP_014843848.1 1682364..1683227(+) (pilD) [Legionella pneumophila subsp. pneumophila]
MINALIINYPWFMYLVVGLFSLAVGSLLNVIIYRLPIILQEEWKEQCCELFQLEQRKEKIKLNLFLPRSFCPHCKAMVKA
WQNIPLLSYILLRGRCYQCDSPISIRYPFVETLTTVLSLYASWHFGFTIQLLFALLAIWILISLVFIDLDHQLLPDSLTL
GLLWIGLIANTQNIFVSLDVAVLSCAGAYLALWLFINLFYLMTGKVGMGHGDFKLFAAFGAWLGWMYLPLILLISSITGA
IIGLIYLKINGKSRDTAIPFGPFLCISGLIAMFWGDSIINWYIGYWM

Nucleotide

• Length: 864 bp

>NTDB_id=52170 LPV_RS07620 WP_014843848.1 1682364..1683227(+) (pilD) [Legionella pneumophila subsp. pneumophila]
ATGATAAATGCACTAATAATCAATTATCCATGGTTTATGTATTTAGTCGTTGGACTCTTTTCTCTAGCTGTTGGAAGTTT
GCTTAATGTGATAATCTATCGCTTACCAATTATTTTGCAGGAAGAGTGGAAAGAGCAATGCTGTGAGCTATTCCAGCTTG
AACAGCGAAAAGAAAAAATAAAACTTAATTTATTTTTACCACGTTCTTTTTGCCCTCATTGTAAAGCGATGGTTAAAGCG
TGGCAGAATATTCCTCTGTTAAGCTATATTTTGTTAAGAGGACGCTGTTACCAATGTGATAGTCCAATTTCAATTCGCTA
CCCTTTTGTTGAGACTCTGACCACAGTTTTATCCTTATACGCCAGTTGGCATTTTGGGTTTACAATACAACTATTATTTG
CTTTATTAGCTATCTGGATATTAATATCACTTGTTTTTATTGATCTTGATCATCAATTACTCCCTGATAGCCTCACTTTA
GGGCTTTTATGGATTGGCCTTATTGCTAATACCCAGAATATATTTGTTAGTCTTGACGTTGCTGTATTAAGCTGTGCTGG
CGCCTATTTAGCCTTATGGTTATTCATTAATCTGTTTTATCTGATGACAGGTAAAGTAGGTATGGGACATGGGGATTTCA
AATTATTTGCAGCATTTGGTGCATGGCTTGGATGGATGTATTTACCATTAATTCTACTAATATCTTCAATAACCGGGGCT
ATCATTGGTTTGATTTATTTAAAGATAAATGGTAAATCAAGAGATACTGCAATACCATTTGGCCCTTTTCTTTGCATTTC
TGGATTAATAGCTATGTTTTGGGGAGACTCAATTATCAATTGGTATATAGGTTATTGGATGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (19-125)

• Type IV leader peptidase family (Peptidase_A24) (136-244)

3D structure

• AlphaFold DB: I7HUK3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	49.11	97.909	0.481
pilD	Acinetobacter nosocomialis M2	48.352	95.122	0.46
pilD	Acinetobacter baumannii D1279779	47.636	95.819	0.456
pilD	Vibrio campbellii strain DS40M4	45.683	96.864	0.443
pilD	Neisseria gonorrhoeae MS11	42.806	96.864	0.415