Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LPO_RS13710 Genome accession   NC_018139
Coordinates   3051021..3051680 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3046021..3056680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPO_RS13695 (LPO_2921) - 3046695..3047354 (+) 660 WP_011947560.1 hypothetical protein -
  LPO_RS13700 (LPO_2922) lcl 3047522..3049129 (+) 1608 WP_014842692.1 collagen-like adhesin Lcl -
  LPO_RS13705 (LPO_2923) uvrC 3049153..3051009 (-) 1857 WP_014842693.1 excinuclease ABC subunit UvrC -
  LPO_RS13710 (LPO_2924) letA 3051021..3051680 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  LPO_RS13715 (LPO_2925) phhA 3051805..3052623 (-) 819 WP_014842694.1 phenylalanine 4-monooxygenase -
  LPO_RS13720 (LPO_2926) - 3053063..3054160 (+) 1098 WP_014842695.1 competence/damage-inducible protein A -
  LPO_RS13725 (LPO_2927) cgtA 3054119..3055144 (-) 1026 WP_014842696.1 Obg family GTPase CgtA -
  LPO_RS13730 (LPO_2928) rpmA 3055359..3055637 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  LPO_RS13735 (LPO_2929) rplU 3055650..3055961 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=52148 LPO_RS13710 WP_011216518.1 3051021..3051680(-) (letA) [Legionella pneumophila subsp. pneumophila]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=52148 LPO_RS13710 WP_011216518.1 3051021..3051680(-) (letA) [Legionella pneumophila subsp. pneumophila]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTGGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTGAAAACCCACTCCCCTGATGTCGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACACGTCGCTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCC
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGCGCTATGGGATACCTTACTAAAGAGTCCGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCCAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTCCAGGAGTCTCAGGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCGGATAGATTATTTTTAAGTAGTAAAACTATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment