Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SMUGS5_RS01070 Genome accession   NC_018089
Coordinates   210736..211458 (+) Length   240 a.a.
NCBI ID   WP_002263984.1    Uniprot ID   A0AAX1K0W7
Organism   Streptococcus mutans GS-5     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 205736..216458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS01055 (SMUGS5_00940) - 206137..207690 (-) 1554 WP_014834802.1 ABC transporter substrate-binding protein/permease -
  SMUGS5_RS01060 (SMUGS5_00945) - 207842..209743 (+) 1902 WP_002280733.1 DUF2207 domain-containing protein -
  SMUGS5_RS01065 (SMUGS5_00950) - 209801..210646 (+) 846 WP_002280732.1 undecaprenyl-diphosphate phosphatase -
  SMUGS5_RS01070 (SMUGS5_00955) mecA 210736..211458 (+) 723 WP_002263984.1 adaptor protein MecA Regulator
  SMUGS5_RS01075 (SMUGS5_00960) rgpG 211464..212624 (+) 1161 WP_002262748.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  SMUGS5_RS01080 (SMUGS5_00965) sufC 212698..213468 (+) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  SMUGS5_RS01085 (SMUGS5_00970) sufD 213506..214768 (+) 1263 WP_014834803.1 Fe-S cluster assembly protein SufD -
  SMUGS5_RS01090 (SMUGS5_00975) - 214773..216002 (+) 1230 WP_002271229.1 cysteine desulfurase -
  SMUGS5_RS01095 (SMUGS5_00980) sufU 215989..216423 (+) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28028.63 Da        Isoelectric Point: 4.2340

>NTDB_id=52007 SMUGS5_RS01070 WP_002263984.1 210736..211458(+) (mecA) [Streptococcus mutans GS-5]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEIEKREEEKTQQEKGETKEKRDYVHFVLDFPNIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=52007 SMUGS5_RS01070 WP_002263984.1 210736..211458(+) (mecA) [Streptococcus mutans GS-5]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATACTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGGACAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCCCCGGAGGATTTCTTTAATACCTT
GGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAGGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTAATATTCAGCAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCGAAGATAAACCTGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

99.583

100

0.996
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.571

100

0.496
  mecA Streptococcus pneumoniae D39

48.571

100

0.496
  mecA Streptococcus pneumoniae R6

48.571

100

0.496
  mecA Streptococcus pneumoniae TIGR4

48.571

100

0.496

Multiple sequence alignment