Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   JEQ25_RS06635 Genome accession   NZ_CP066380
Coordinates   1247377..1248033 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis strain ID-A05     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1242377..1253033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JEQ25_RS06605 (JEQ25_06550) oppF 1242840..1243757 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  JEQ25_RS06610 (JEQ25_06555) yjbB 1243865..1245082 (+) 1218 WP_080478438.1 MFS transporter -
  JEQ25_RS06615 (JEQ25_06560) yjbC 1245247..1245825 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  JEQ25_RS06620 (JEQ25_06565) spx 1246006..1246401 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  JEQ25_RS06625 (JEQ25_06570) yjbE 1246444..1247100 (-) 657 WP_003232944.1 TerC family protein -
  JEQ25_RS06630 (JEQ25_06575) - 1247270..1247410 (+) 141 WP_119122854.1 hypothetical protein -
  JEQ25_RS06635 (JEQ25_06580) mecA 1247377..1248033 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  JEQ25_RS06640 (JEQ25_06585) - 1248028..1248150 (-) 123 WP_003245684.1 hypothetical protein -
  JEQ25_RS06645 (JEQ25_06590) coiA 1248194..1249345 (+) 1152 WP_046380934.1 competence protein CoiA Machinery gene
  JEQ25_RS06650 (JEQ25_06595) pepF 1249575..1251404 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  JEQ25_RS06655 (JEQ25_06600) - 1251442..1251609 (-) 168 WP_003244944.1 hypothetical protein -
  JEQ25_RS06660 (JEQ25_06605) spxH 1251923..1252822 (-) 900 WP_024573348.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=519811 JEQ25_RS06635 WP_003245194.1 1247377..1248033(+) (mecA) [Bacillus subtilis strain ID-A05]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=519811 JEQ25_RS06635 WP_003245194.1 1247377..1248033(+) (mecA) [Bacillus subtilis strain ID-A05]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1