Detailed information    

insolico Bioinformatically predicted

Overview

Name   hdrM   Type   Regulator
Locus tag   IGS65_RS09175 Genome accession   NZ_CP066294
Coordinates   1887783..1888469 (-) Length   228 a.a.
NCBI ID   WP_192072393.1    Uniprot ID   A0AAX1K3A8
Organism   Streptococcus mutans strain 27-3     
Function   repress competence development; negative regulate HdrR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1882783..1893469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS65_RS09150 (IGS65_009150) - 1885265..1885510 (+) 246 WP_002276385.1 hypothetical protein -
  IGS65_RS09155 (IGS65_009155) rpsF 1885666..1885956 (+) 291 WP_002276384.1 30S ribosomal protein S6 -
  IGS65_RS09160 (IGS65_009160) ssbA 1885974..1886468 (+) 495 WP_002261867.1 single-stranded DNA-binding protein Machinery gene
  IGS65_RS09165 (IGS65_009165) rpsR 1886498..1886737 (+) 240 WP_000068664.1 30S ribosomal protein S18 -
  IGS65_RS09170 (IGS65_009170) - 1887056..1887775 (+) 720 WP_192072394.1 TraX family protein -
  IGS65_RS09175 (IGS65_009175) hdrM 1887783..1888469 (-) 687 WP_192072393.1 hdrR negative regulator HdrM Regulator
  IGS65_RS09180 (IGS65_009180) hdrR 1888466..1888822 (-) 357 WP_002268419.1 LytTR family transcriptional regulator HdrR Regulator
  IGS65_RS09185 (IGS65_009185) - 1888961..1889623 (-) 663 WP_002265267.1 DUF1129 domain-containing protein -
  IGS65_RS09190 (IGS65_009190) - 1889760..1890704 (-) 945 WP_192072392.1 magnesium transporter CorA family protein -
  IGS65_RS09195 (IGS65_009195) - 1891104..1891326 (-) 223 Protein_1781 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26087.14 Da        Isoelectric Point: 6.7581

>NTDB_id=519168 IGS65_RS09175 WP_192072393.1 1887783..1888469(-) (hdrM) [Streptococcus mutans strain 27-3]
MKKNYFWYGLLGLLALYLITIAFIPGFHIFFSNMLMLALFFMLIALSNRSIFFFFLALGFLSIYLKDIFHFDYSTGPLFT
GIIIIGVILNSFLKPHYSYSYKGNHYFNMKQNANYIDNETDVFLKTLFSENTSYVTSQELNKIIIDTKFGEQSVDISQAQ
FMTDSPEIHIDVSFGETNLRIPNNWKIINKTHSPFASISFSGFPSTNGDFINVTLTGTVAMGSLNIQY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=519168 IGS65_RS09175 WP_192072393.1 1887783..1888469(-) (hdrM) [Streptococcus mutans strain 27-3]
ATGAAAAAAAATTATTTTTGGTACGGTCTGCTTGGGCTTCTCGCACTTTACCTTATTACTATTGCTTTTATCCCGGGATT
TCATATTTTCTTTAGCAACATGTTGATGTTGGCTCTGTTCTTTATGTTAATAGCTTTGAGTAACAGGAGTATCTTCTTTT
TCTTTCTAGCCTTAGGTTTTCTTAGTATCTACTTGAAAGATATCTTTCATTTTGACTATTCTACCGGACCGCTTTTTACG
GGTATAATCATTATCGGCGTTATCTTAAATAGTTTCCTCAAACCACACTATTCTTATTCTTATAAAGGAAATCATTATTT
TAATATGAAACAAAATGCTAACTACATTGATAACGAAACAGATGTCTTTTTAAAAACACTTTTTTCTGAAAATACCAGTT
ATGTGACTTCTCAAGAATTAAATAAAATTATTATTGATACTAAGTTTGGAGAACAATCTGTTGATATCTCTCAAGCTCAA
TTTATGACAGATTCTCCCGAAATTCATATAGATGTTAGCTTTGGTGAAACCAATCTGCGTATTCCAAACAACTGGAAAAT
CATCAATAAAACTCACTCCCCCTTTGCTTCCATTTCATTTTCAGGTTTTCCTAGCACAAATGGTGATTTTATTAACGTTA
CATTGACTGGAACAGTGGCTATGGGATCTCTAAACATTCAATATTAA

Domains

Predicted by InterproScan.

Cell wall-active antibiotics response 4TMS YvqF (LiaF-like_C)

(128-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hdrM Streptococcus mutans UA159

99.123

100

0.991