Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   IGS65_RS05435 Genome accession   NZ_CP066294
Coordinates   1111654..1112955 (-) Length   433 a.a.
NCBI ID   WP_002264401.1    Uniprot ID   A0AAX1JZQ7
Organism   Streptococcus mutans strain 27-3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1106654..1117955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS65_RS05410 (IGS65_005410) - 1106712..1107347 (+) 636 WP_002285302.1 hypothetical protein -
  IGS65_RS05415 (IGS65_005415) - 1107427..1109127 (-) 1701 WP_192072089.1 hypothetical protein -
  IGS65_RS05420 (IGS65_005420) - 1109147..1110241 (-) 1095 WP_168745521.1 hypothetical protein -
  IGS65_RS05425 (IGS65_005425) raiA 1110365..1110913 (-) 549 WP_002263024.1 ribosome-associated translation inhibitor RaiA -
  IGS65_RS05430 (IGS65_005430) - 1110992..1111657 (-) 666 WP_002270131.1 ComF family protein -
  IGS65_RS05435 (IGS65_005435) comFA/cflA 1111654..1112955 (-) 1302 WP_002264401.1 DEAD/DEAH box helicase Machinery gene
  IGS65_RS05440 (IGS65_005440) - 1113028..1113657 (+) 630 WP_002267951.1 YigZ family protein -
  IGS65_RS05445 (IGS65_005445) cysK 1113748..1114674 (+) 927 WP_002263028.1 cysteine synthase A -
  IGS65_RS05450 (IGS65_005450) - 1115008..1116099 (-) 1092 WP_002267044.1 glycerol dehydrogenase -
  IGS65_RS05455 (IGS65_005455) - 1116138..1116806 (-) 669 WP_002263030.1 fructose-6-phosphate aldolase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49471.64 Da        Isoelectric Point: 10.0270

>NTDB_id=519128 IGS65_RS05435 WP_002264401.1 1111654..1112955(-) (comFA/cflA) [Streptococcus mutans strain 27-3]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRGKLPRSFLQQIRIQRQTQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=519128 IGS65_RS05435 WP_002264401.1 1111654..1112955(-) (comFA/cflA) [Streptococcus mutans strain 27-3]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGGTAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGACTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACTTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAAATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

Type III restriction enzyme, res subunit (ResIII)

(94-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae D39

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae R6

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae TIGR4

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

58.782

98.614

0.58
  comFA/cflA Streptococcus mitis SK321

58.314

98.614

0.575
  comFA Lactococcus lactis subsp. cremoris KW2

51.777

90.993

0.471
  comFA Latilactobacillus sakei subsp. sakei 23K

38.967

98.383

0.383