Detailed information NTG0519117

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: IGS65_RS03455
• Genome accession: NZ_CP066294
• Coordinates: 692705..693937 (-)
• Length: 410 a.a.
• NCBI ID: WP_002262816.1
• Uniprot ID: A0AAX1K4W9
• Organism: Streptococcus mutans strain 27-3
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 687705..698937

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGS65_RS03435 (IGS65_003435)	-	688035..689297 (+)	1263	WP_002283146.1	PLP-dependent aminotransferase family protein	-
IGS65_RS03440 (IGS65_003440)	mmuM	689431..690381 (-)	951	WP_002286716.1	homocysteine S-methyltransferase	-
IGS65_RS03445 (IGS65_003445)	-	690391..691767 (-)	1377	WP_002272474.1	amino acid permease	-
IGS65_RS03450 (IGS65_003450)	yihA	692096..692689 (-)	594	WP_002275241.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
IGS65_RS03455 (IGS65_003455)	clpX	692705..693937 (-)	1233	WP_002262816.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
IGS65_RS03460 (IGS65_003460)	-	693962..694132 (-)	171	WP_002262815.1	hypothetical protein	-
IGS65_RS03465 (IGS65_003465)	-	694150..694662 (-)	513	WP_002262814.1	dihydrofolate reductase	-
IGS65_RS03470 (IGS65_003470)	pnuC	694747..695526 (-)	780	WP_002264318.1	nicotinamide riboside transporter PnuC	-
IGS65_RS03475 (IGS65_003475)	-	695643..696482 (-)	840	WP_002267987.1	thymidylate synthase	-
IGS65_RS03480 (IGS65_003480)	-	696690..697865 (+)	1176	WP_192072201.1	hydroxymethylglutaryl-CoA synthase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45181.65 Da
• Isoelectric Point: 4.4495

>NTDB_id=519117 IGS65_RS03455 WP_002262816.1 692705..693937(-) (clpX) [Streptococcus mutans strain 27-3]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide

• Length: 1233 bp

>NTDB_id=519117 IGS65_RS03455 WP_002262816.1 692705..693937(-) (clpX) [Streptococcus mutans strain 27-3]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTGTTGGCAATACTAGACAGTTATGTTATCGGTCAGGACCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATT
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATCCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACGCTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACCGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	100	100	1
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	97.805	0.578