Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SCIM_RS06835 Genome accession   NC_018073
Coordinates   1410514..1411203 (-) Length   229 a.a.
NCBI ID   WP_003077963.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1405514..1416203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS06815 (SCIM_1232) - 1406029..1406472 (+) 444 WP_003076375.1 hypothetical protein -
  SCIM_RS06820 (SCIM_1233) - 1406524..1407339 (-) 816 WP_003076645.1 endonuclease/exonuclease/phosphatase family protein -
  SCIM_RS06825 (SCIM_1234) - 1407357..1409546 (-) 2190 WP_014829751.1 PTS transporter subunit IIBC -
  SCIM_RS06830 (SCIM_1235) - 1409758..1410207 (-) 450 Protein_1349 PTS glucose transporter subunit IIA -
  SCIM_RS06835 (SCIM_1236) covR 1410514..1411203 (-) 690 WP_003077963.1 DNA-binding response regulator Regulator
  SCIM_RS06840 (SCIM_1237) gndA 1411212..1412636 (-) 1425 WP_003077965.1 NADP-dependent phosphogluconate dehydrogenase -
  SCIM_RS06845 (SCIM_1238) - 1412728..1413264 (-) 537 WP_003077972.1 YceD family protein -
  SCIM_RS06850 (SCIM_1239) - 1413452..1414678 (+) 1227 WP_003077939.1 hypothetical protein -
  SCIM_RS06855 (SCIM_1240) htpX 1414781..1415677 (-) 897 WP_003068114.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26572.65 Da        Isoelectric Point: 6.6513

>NTDB_id=51881 SCIM_RS06835 WP_003077963.1 1410514..1411203(-) (covR) [Streptococcus intermedius JTH08]
MGKRILLVENEKKLAQFISLELQNEGYRVDLFETGKDALTSARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIVMDLVGKISAIFRGRDFIDHHCSQMKISTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHHALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=51881 SCIM_RS06835 WP_003077963.1 1410514..1411203(-) (covR) [Streptococcus intermedius JTH08]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTAGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTTTTGAAACGGGAAAAGATGCTTTAACATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTAAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTGAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGT
GATGGACTTGGTCGGAAAAATTTCTGCTATTTTTCGTGGGCGTGATTTTATTGATCATCATTGTAGTCAGATGAAAATTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACCGTATATCGAGGGAATGAAATAATTTCTTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCATGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCTGTTGAGACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATCAAAACTGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)

Response regulator receiver domain (Response_reg)

(5-82)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45

Multiple sequence alignment