Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   I6I02_RS06590 Genome accession   NZ_CP066093
Coordinates   1454137..1455363 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1449137..1460363
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS06560 (I6I02_06560) plsY 1449482..1450123 (+) 642 WP_002890350.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  I6I02_RS06565 (I6I02_06565) - 1450241..1450618 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  I6I02_RS06570 (I6I02_06570) - 1450693..1450947 (-) 255 WP_002886199.1 DUF1912 family protein -
  I6I02_RS06575 (I6I02_06575) mmuM 1451060..1452010 (-) 951 WP_002885890.1 homocysteine S-methyltransferase -
  I6I02_RS06580 (I6I02_06580) - 1452022..1453398 (-) 1377 WP_080610350.1 amino acid permease -
  I6I02_RS06585 (I6I02_06585) yihA 1453528..1454127 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  I6I02_RS06590 (I6I02_06590) clpX 1454137..1455363 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  I6I02_RS06595 (I6I02_06595) - 1455381..1455551 (-) 171 WP_002886174.1 hypothetical protein -
  I6I02_RS06600 (I6I02_06600) - 1455556..1456059 (-) 504 WP_037597549.1 dihydrofolate reductase -
  I6I02_RS06605 (I6I02_06605) - 1456168..1457028 (-) 861 WP_198463290.1 thymidylate synthase -
  I6I02_RS06610 (I6I02_06610) - 1457501..1458667 (+) 1167 WP_198463291.1 hydroxymethylglutaryl-CoA synthase -
  I6I02_RS06615 (I6I02_06615) - 1458669..1459940 (+) 1272 WP_198463292.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=517365 I6I02_RS06590 WP_002890340.1 1454137..1455363(-) (clpX) [Streptococcus salivarius strain FDAARGOS_1045]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=517365 I6I02_RS06590 WP_002890340.1 1454137..1455363(-) (clpX) [Streptococcus salivarius strain FDAARGOS_1045]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAATTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACAGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGAATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGCCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCTGCCCTGGAACAGTTAACGGTGGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGAGTTGAACTTGAGTTTGACCAAGA
TGCTCTTGAAGCTATTGCAAGTAAGGCAATCGAACGTAAGACTGGTGCACGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566