Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6H74_RS04210 Genome accession   NZ_CP066069
Coordinates   841961..843286 (+) Length   441 a.a.
NCBI ID   WP_015017291.1    Uniprot ID   A0A9X8T4I6
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 836961..848286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS04185 (I6H74_04180) - 837638..838279 (+) 642 WP_014612503.1 response regulator transcription factor -
  I6H74_RS04190 (I6H74_04185) - 838316..839716 (+) 1401 WP_046177466.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6H74_RS04195 (I6H74_04190) - 839716..840075 (+) 360 WP_003056775.1 S1 RNA-binding domain-containing protein -
  I6H74_RS04200 (I6H74_04195) cysK 840228..841163 (-) 936 WP_003062335.1 cysteine synthase A -
  I6H74_RS04205 (I6H74_04200) - 841267..841905 (-) 639 WP_115256985.1 YigZ family protein -
  I6H74_RS04210 (I6H74_04205) comFA/cflA 841961..843286 (+) 1326 WP_015017291.1 DEAD/DEAH box helicase Machinery gene
  I6H74_RS11020 (I6H74_04210) - 843258..843923 (+) 666 WP_065358974.1 ComF family protein -
  I6H74_RS04220 (I6H74_04215) raiA 844003..844551 (+) 549 WP_003061817.1 ribosome-associated translation inhibitor RaiA -
  I6H74_RS04225 (I6H74_04220) - 844681..845661 (+) 981 WP_115257105.1 IS30 family transposase -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49283.45 Da        Isoelectric Point: 9.7069

>NTDB_id=517100 I6H74_RS04210 WP_015017291.1 841961..843286(+) (comFA/cflA) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVAIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYLNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=517100 I6H74_RS04210 WP_015017291.1 841961..843286(+) (comFA/cflA) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGGAAGGTATCGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAGCCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGTGGCACTTACTACTGCCGCTTCTGTCTCGTTTTTGGTCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACGCCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGAGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCCAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGGGTTACTCTTTTACATGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCAGCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAACTAGAGAAGTTGACATTAGCTAGACGATTCCACGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGTCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAACAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGCCTT
TCGTCAAGGAAAGAAAGGTATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGCGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTGGGGAGATCTATCGAAAGG
CCAACAGGGAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTTGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-396)

DEAD/DEAH box helicase (DEAD)

(99-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae D39

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae R6

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae TIGR4

53.302

96.145

0.512
  comFA/cflA Streptococcus mitis NCTC 12261

51.852

97.959

0.508
  comFA/cflA Streptococcus mitis SK321

52.214

97.279

0.508
  comFA Lactococcus lactis subsp. cremoris KW2

46.465

89.796

0.417
  comFA Latilactobacillus sakei subsp. sakei 23K

37.587

97.732

0.367