Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   I6H74_RS01310 Genome accession   NZ_CP066069
Coordinates   248893..248988 (-) Length   31 a.a.
NCBI ID   WP_198455558.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 249075..261464 248893..248988 flank 87


Gene organization within MGE regions


Location: 248893..261464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS01310 comS 248893..248988 (-) 96 WP_198455558.1 quorum-sensing system DWW-type pheromone Regulator
  I6H74_RS01315 (I6H74_01310) comR 249075..249986 (-) 912 WP_115256701.1 XRE family transcriptional regulator Regulator
  I6H74_RS01320 (I6H74_01315) purB 250128..251420 (-) 1293 WP_022554088.1 adenylosuccinate lyase -
  I6H74_RS01325 (I6H74_01320) - 251605..253464 (-) 1860 WP_015016520.1 DUF262 domain-containing protein -
  I6H74_RS01330 (I6H74_01325) purK 253483..254556 (-) 1074 WP_115256700.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  I6H74_RS01335 (I6H74_01330) purE 254543..255031 (-) 489 WP_046177508.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  I6H74_RS01340 (I6H74_01335) - 255462..256325 (+) 864 WP_046177583.1 IS982 family transposase -
  I6H74_RS01345 (I6H74_01340) purD 256636..257898 (-) 1263 WP_046177522.1 phosphoribosylamine--glycine ligase -
  I6H74_RS01350 (I6H74_01345) - 258182..259309 (+) 1128 WP_003055557.1 SH3 domain-containing protein -
  I6H74_RS01355 (I6H74_01350) purH 259389..260933 (-) 1545 WP_046177523.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -
  I6H74_RS01360 (I6H74_01355) - 260952..261464 (-) 513 WP_015057184.1 VanZ family protein -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3929.72 Da        Isoelectric Point: 10.1669

>NTDB_id=517082 I6H74_RS01310 WP_198455558.1 248893..248988(-) (comS) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MFKRYHYYFILTAMLAFKAAQMISQVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=517082 I6H74_RS01310 WP_198455558.1 248893..248988(-) (comS) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGTTCAAAAGATATCACTACTATTTTATACTTACTGCTATGTTAGCATTTAAAGCAGCTCAGATGATAAGTCAAGTGGA
TTGGTGGCGTTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

61.29

100

0.613
  comS Streptococcus pyogenes MGAS315

38.71

100

0.387