Detailed information NTG0517013

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6I28_RS02020
• Genome accession: NZ_CP066062
• Coordinates: 394225..395268 (-)
• Length: 347 a.a.
• NCBI ID: WP_002472963.1
• Uniprot ID: A0A1Z3TZK4
• Organism: Staphylococcus pettenkoferi strain FDAARGOS_1071
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 389225..400268

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I28_RS01990 (I6I28_01990)	-	390139..390339 (-)	201	WP_002472952.1	DUF1128 family protein	-
I6I28_RS01995 (I6I28_01995)	-	390474..390938 (+)	465	WP_049406397.1	low molecular weight protein-tyrosine-phosphatase	-
I6I28_RS02000 (I6I28_02000)	-	390943..391245 (+)	303	WP_002472981.1	hypothetical protein	-
I6I28_RS02005 (I6I28_02005)	-	391503..392484 (+)	982	Protein_362	YihY/virulence factor BrkB family protein	-
I6I28_RS02010 (I6I28_02010)	-	392945..393513 (+)	569	Protein_363	beta-class carbonic anhydrase	-
I6I28_RS02015 (I6I28_02015)	vraR	393606..394235 (-)	630	WP_049406399.1	response regulator transcription factor	Regulator
I6I28_RS02020 (I6I28_02020)	vraS	394225..395268 (-)	1044	WP_002472963.1	sensor histidine kinase	Regulator
I6I28_RS02025 (I6I28_02025)	liaF	395265..395966 (-)	702	WP_002472955.1	cell wall-active antibiotics response protein LiaF	-
I6I28_RS02030 (I6I28_02030)	-	396140..396535 (-)	396	WP_049406401.1	hypothetical protein	-
I6I28_RS02035 (I6I28_02035)	map	396696..397460 (-)	765	WP_002472950.1	type I methionyl aminopeptidase	-
I6I28_RS02040 (I6I28_02040)	-	397617..398606 (+)	990	WP_049406403.1	FUSC family protein	-
I6I28_RS02045 (I6I28_02045)	-	398726..399448 (-)	723	WP_049406404.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40013.42 Da
• Isoelectric Point: 5.8559

>NTDB_id=517013 I6I28_RS02020 WP_002472963.1 394225..395268(-) (vraS) [Staphylococcus pettenkoferi strain FDAARGOS_1071]
MNHYIRAIGSMLILVYSMLFAFLFIDKIFVNIIYFQGMFYTQIFGIPVFLFLNIVIILLCIIVGSVLAYKINQQNHWLQE
QIERSIEGETVGINDQNIELYNETIALYQTLVPLNQEVHKLRMKTQNLTNESYNINDKKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESTLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHQI
EDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTIELFNKEDYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAN
FHIVSLPDSGTRIEVKAPLNKEELSDD

Nucleotide

• Length: 1044 bp

>NTDB_id=517013 I6I28_RS02020 WP_002472963.1 394225..395268(-) (vraS) [Staphylococcus pettenkoferi strain FDAARGOS_1071]
GTGAATCACTACATAAGAGCCATAGGATCGATGTTAATCCTCGTCTACAGTATGCTTTTCGCATTTCTCTTTATTGATAA
AATATTTGTGAATATCATTTATTTTCAAGGCATGTTCTATACGCAAATATTTGGTATTCCGGTATTTTTATTCTTAAATA
TCGTTATCATCTTACTTTGTATCATCGTGGGTTCTGTGTTAGCTTATAAGATTAATCAACAGAACCACTGGCTTCAAGAA
CAAATCGAACGTTCGATCGAAGGTGAAACAGTCGGTATTAACGATCAAAATATTGAACTGTATAATGAAACGATTGCGCT
CTATCAAACGTTGGTGCCACTCAACCAAGAAGTACATAAATTACGTATGAAGACCCAGAATTTAACGAATGAGTCATATA
ATATCAATGATAAGAAAGTTAAGAAAATCATCGAAGACGAGCGTCAACGTTTAGCACGAGAATTACACGACTCAGTGAGT
CAGCAACTGTTTGCAGCAAGTATGATGTTGTCAGCAATCAAGGAATCGACATTAGAGCCACCGCTCGATCAACAAATACC
CACGTTAGAAAAAATGGTACAAGATTCACAACTTGAAATGAGAGCCTTACTTTTACATCTTAGACCTATCGGATTGAAAG
ATAAATCACTAGGAGAGGGAATAAAAGATTTAGTTGTTGATCTTCAGAAGAAAGTGCCGATGAAAGTGGTTCACCAAATA
GAAGATTTTAAAGTCCCTAAAGGCATTGAAGATCATTTATTCCGCATTACTCAAGAGGCGATTTCAAACACCTTACGTCA
CTCTAACGGAACGAAAGTAACGATTGAATTATTCAATAAAGAAGATTATTTACTATTACGTATACAAGACGACGGTAAAG
GATTTAACGTAGATGATAAAGTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCGCTAGAAATCGGCGCGAAC
TTCCACATTGTATCCTTGCCAGATTCAGGGACACGTATCGAAGTGAAAGCACCGTTGAACAAGGAGGAATTAAGTGATGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A1Z3TZK4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	89.914	100	0.899