Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6H78_RS03700 Genome accession   NZ_CP066059
Coordinates   768593..769282 (-) Length   229 a.a.
NCBI ID   WP_198460113.1    Uniprot ID   A0A7T4IU78
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 763593..774282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS03680 (I6H78_03680) - 764575..765582 (-) 1008 WP_198460109.1 phosphomevalonate kinase -
  I6H78_RS03685 (I6H78_03685) mvaD 765569..766522 (-) 954 WP_198460110.1 diphosphomevalonate decarboxylase -
  I6H78_RS03690 (I6H78_03690) mvk 766504..767382 (-) 879 WP_198460111.1 mevalonate kinase -
  I6H78_RS03695 (I6H78_03695) cbpF 767501..768493 (-) 993 WP_198460112.1 choline-binding protein CbpF -
  I6H78_RS03700 (I6H78_03700) covR 768593..769282 (-) 690 WP_198460113.1 DNA-binding response regulator Regulator
  I6H78_RS03705 (I6H78_03705) gndA 769294..770718 (-) 1425 WP_198460114.1 NADP-dependent phosphogluconate dehydrogenase -
  I6H78_RS03710 (I6H78_03710) mapZ 770794..772236 (-) 1443 WP_198460115.1 cell division site-positioning protein MapZ -
  I6H78_RS03715 (I6H78_03715) - 772249..773406 (-) 1158 WP_198460116.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  I6H78_RS03725 (I6H78_03725) gpsB 773892..774221 (-) 330 WP_007518509.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26783.97 Da        Isoelectric Point: 7.4139

>NTDB_id=516941 I6H78_RS03700 WP_198460113.1 768593..769282(-) (covR) [Streptococcus oralis strain FDAARGOS_1021]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHLEELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=516941 I6H78_RS03700 WP_198460113.1 768593..769282(-) (covR) [Streptococcus oralis strain FDAARGOS_1021]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCAGCCTCAGTGATCATGGTCTTG
GACCATCTCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGCCAGATGAAGGTCC
CAACGTCTTACCGCAATTTACGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTATTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATTGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGGTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4IU78

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463