Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6I32_RS03630 Genome accession   NZ_CP066041
Coordinates   745366..746055 (-) Length   229 a.a.
NCBI ID   WP_198464949.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 740366..751055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS03605 (I6I32_03605) - 740423..741430 (-) 1008 WP_198464945.1 phosphomevalonate kinase -
  I6I32_RS03610 (I6I32_03610) mvaD 741417..742370 (-) 954 WP_198464946.1 diphosphomevalonate decarboxylase -
  I6I32_RS03615 (I6I32_03615) mvk 742352..743230 (-) 879 WP_198464947.1 mevalonate kinase -
  I6I32_RS03620 (I6I32_03620) cbpC 743348..744367 (-) 1020 WP_198464948.1 choline-binding protein CbpC -
  I6I32_RS03625 (I6I32_03625) - 744385..745266 (-) 882 WP_000713620.1 N-acetylmuramoyl-L-alanine amidase family protein -
  I6I32_RS03630 (I6I32_03630) covR 745366..746055 (-) 690 WP_198464949.1 DNA-binding response regulator Regulator
  I6I32_RS03635 (I6I32_03635) gndA 746067..747491 (-) 1425 WP_000158772.1 NADP-dependent phosphogluconate dehydrogenase -
  I6I32_RS03640 (I6I32_03640) mapZ 747567..749012 (-) 1446 WP_198464950.1 cell division site-positioning protein MapZ -
  I6I32_RS03645 (I6I32_03645) - 749025..750182 (-) 1158 WP_198464951.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  I6I32_RS03655 (I6I32_03655) gpsB 750668..750997 (-) 330 WP_000146523.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26808.97 Da        Isoelectric Point: 8.0271

>NTDB_id=516632 I6I32_RS03630 WP_198464949.1 745366..746055(-) (covR) [Streptococcus oralis strain FDAARGOS_1075]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=516632 I6I32_RS03630 WP_198464949.1 745366..746055(-) (covR) [Streptococcus oralis strain FDAARGOS_1075]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGACAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCTGCCTCAGTGATTATGGTCTTA
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATAGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

47.368

99.563

0.472