Detailed information NTG0516497

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: I6H77_RS08515
• Genome accession: NZ_CP066021
• Coordinates: 1772911..1774260 (+)
• Length: 449 a.a.
• NCBI ID: WP_000568721.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_1020
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1767911..1779260

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H77_RS08490 (I6H77_08490)	-	1768164..1768982 (+)	819	WP_000799063.1	NAD kinase	-
I6H77_RS08495 (I6H77_08495)	-	1768979..1769875 (+)	897	WP_001210025.1	RluA family pseudouridine synthase	-
I6H77_RS08500 (I6H77_08500)	pta	1769919..1770893 (+)	975	WP_000451577.1	phosphate acetyltransferase	-
I6H77_RS08505 (I6H77_08505)	mutY	1770976..1772154 (+)	1179	WP_000886126.1	A/G-specific adenine glycosylase	-
I6H77_RS08510 (I6H77_08510)	micA	1772211..1772918 (+)	708	WP_000722058.1	response regulator YycF	Regulator
I6H77_RS08515 (I6H77_08515)	micB	1772911..1774260 (+)	1350	WP_000568721.1	cell wall metabolism sensor histidine kinase VicK	Regulator
I6H77_RS08520 (I6H77_08520)	vicX	1774262..1775071 (+)	810	WP_001290610.1	MBL fold metallo-hydrolase	Regulator
I6H77_RS08525 (I6H77_08525)	-	1775179..1777050 (+)	1872	WP_000150976.1	Eco57I restriction-modification methylase domain-containing protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51607.95 Da
• Isoelectric Point: 4.5770

>NTDB_id=516497 I6H77_RS08515 WP_000568721.1 1772911..1774260(+) (micB) [Streptococcus oralis strain FDAARGOS_1020]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LTIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNTTSQLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide

• Length: 1350 bp

>NTDB_id=516497 I6H77_RS08515 WP_000568721.1 1772911..1774260(+) (micB) [Streptococcus oralis strain FDAARGOS_1020]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGTGATTTTATCTTTATCTTGATTTTACTTGGCTTTATCCTGGTGGT
GACCTTGCTGTTACTGGAAAATCGTCGGGATAATATCCGTCTAAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTGCAAGGAAGTACAGAAATCACCAATATCACCAATAATCTGAACGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAACAGTATTCTTTCTTACATGACAGATGGCGT
TCTTGCGACCAATCGCCGTGGCCAGATTACTATGATCAACGATATGGCCAAGAAACAGCTCGGTGTGCAGAAAGAAGATG
TTCTGAATAAAAGCATCCTCGAATTGCTTAAGATAGAAGATGAGTATGAGTTGCGTGACCTGATTACACAGATTCCTGAG
TTGACGATTGACTCCCAGGATGTGAATGGTGAATATCTAAGCCTTCGTGTACGTTTTGCTCTGGTTCGCCGTGAGTCAGG
TTTTATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAACAGGAGAAGGAAGAGCGTGAGCGAAGACTCTTTGTTT
CTAACGTGAGTCACGAGTTGCGAACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTGGACGAGGGAGCCCTGTAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATACGACAAGTCAGCTAGATGTGGAATTGATTAATTTTACAGCATTCATCACCTTTATTCTCA
ACCGCTTTGATAAGATGAGAAGTCAGGATGACGAGAAAAAATATGAGCTTGTCAGAGATTACCCTATTAATTCAGTTTGG
ATCGAGATTGATACCGATAAGATGACTCAGGTGATTGATAATATTCTTAACAATGCCATTAAGTACTCACCAGATGGTGG
GAAAATCACTGTCAGCATGAAAACTACTGATGACCAGATGATTTTATCCATCAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCTAAGATTTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGGGCTCAAGGTGGAACTGGTCTAGGT
CTGGCGATCGCAAAAGAAATCATCAAACAACACAATGGCTTTATATGGGCCAAAAGTGAATACGGTAAGGGCTCAACCTT
TACCATAGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	89.294	97.773	0.873
vicK	Streptococcus mutans UA159	70.896	89.532	0.635