Detailed information NTG0516112

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6H76_RS02770
• Genome accession: NZ_CP065994
• Coordinates: 556076..558310 (-)
• Length: 744 a.a.
• NCBI ID: WP_174221233.1
• Uniprot ID: -
• Organism: Streptococcus infantarius strain FDAARGOS_1019
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 551076..563310

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H76_RS02740 (I6H76_02740)	-	551972..552697 (-)	726	WP_043878303.1	YebC/PmpR family DNA-binding transcriptional regulator	-
I6H76_RS02745 (I6H76_02745)	sodA	552802..553413 (-)	612	WP_006531489.1	superoxide dismutase SodA	-
I6H76_RS02750 (I6H76_02750)	holA	553509..554546 (-)	1038	WP_006531490.1	DNA polymerase III subunit delta	-
I6H76_RS02755 (I6H76_02755)	-	554598..554750 (-)	153	WP_006531491.1	hypothetical protein	-
I6H76_RS02760 (I6H76_02760)	-	554877..555314 (-)	438	WP_223903590.1	hypothetical protein	-
I6H76_RS02765 (I6H76_02765)	-	555377..555904 (-)	528	WP_006531493.1	HD family hydrolase	-
I6H76_RS02770 (I6H76_02770)	comEC/celB	556076..558310 (-)	2235	WP_174221233.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6H76_RS02775 (I6H76_02775)	-	558300..558980 (-)	681	WP_006531495.1	helix-hairpin-helix domain-containing protein	-
I6H76_RS02780 (I6H76_02780)	-	559078..559824 (-)	747	WP_014334451.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
I6H76_RS02785 (I6H76_02785)	-	559932..560693 (+)	762	WP_006531497.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
I6H76_RS02790 (I6H76_02790)	-	560668..560943 (+)	276	WP_006531499.1	GIY-YIG nuclease family protein	-
I6H76_RS02795 (I6H76_02795)	-	560983..562584 (-)	1602	WP_006531501.1	DEAD/DEAH box helicase	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84337.01 Da
• Isoelectric Point: 8.8613

>NTDB_id=516112 I6H76_RS02770 WP_174221233.1 556076..558310(-) (comEC/celB) [Streptococcus infantarius strain FDAARGOS_1019]
MLIKYLPIKPIQLAFLLTLLYYFCFEKVVLCLILLLLALLFLWQQYGWKAWCQVSLCLAFFAIFFLTKANQTEQVYQAAP
AHLTKIQMIPDTISVNGDLLSFRGKEAGQIYQVFYTLKSEKKQEFFKNLNQTMFLSGQVDLEEATPQRNFGGFDYRTYLK
HEGIYRIANLSSITEMRQQSSLSFFERLHELRRQAIVSIQRNFPAPIQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFA
LSGMQVGFFVALFRFIILRLGLRRDYVDILQIPFSLVYAGLTGFSVSVVRSLVQSAFANLGIKKLDNLAYTLMTLFILMP
NFLLTTGGILSFTYAFILSFIDFDELSHYRKILTECLAISLGSLPVLLYFFSVFQPLSLLLTAIFSLAFDTLILPVLTFV
FLLSPLVKITALNPFFVFLETIIKFSKSLVGTPLVFGRPSLGILLLLLLTIGLLYDCYQRKKVAIFLLSLIALLFFQIKH
PLENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKKSWQKRLADSNAERTLIPYLKSRGIGKIDQLVLTHTDTDH
MGDMLEVAKELKIGQVLVSPGSLTKPDFVVKLRQMKTPVRAVFAGDNLPIMGSHLQVLYPIEVGDGSNNDSVVLYGKLLG
KNFLFTGDLEEEGEQQMIATYPNLPVDVLKAGHHGSKGSSSPEFLEHISPQVVLISAGQNNRYKHPHQETLERFQAQNMT
IYRTDEQGAIRFRGLKTWHIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=516112 I6H76_RS02770 WP_174221233.1 556076..558310(-) (comEC/celB) [Streptococcus infantarius strain FDAARGOS_1019]
CTGTTGATTAAGTATCTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCACTTTACTTTATTATTTTTGTTTTGAAAA
AGTGGTGTTATGTCTGATTTTACTCCTGTTAGCCTTGCTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAGG
TTTCACTGTGCTTGGCTTTCTTTGCGATATTTTTCCTGACTAAGGCTAATCAGACAGAACAGGTTTATCAAGCGGCGCCA
GCTCATTTAACAAAAATCCAGATGATTCCTGATACGATTTCGGTTAATGGTGATTTATTATCCTTTCGAGGTAAGGAAGC
TGGGCAGATTTACCAAGTTTTTTATACCTTGAAGTCAGAAAAAAAGCAGGAATTTTTTAAAAATCTTAATCAAACAATGT
TTTTATCAGGGCAGGTGGATTTAGAAGAGGCAACGCCACAGCGGAATTTTGGTGGTTTTGATTACCGCACTTACCTTAAA
CATGAAGGCATTTATCGGATTGCTAATCTTTCTTCGATTACTGAAATGAGACAGCAGAGCTCTTTAAGTTTTTTTGAACG
ACTACATGAACTTAGAAGACAGGCGATTGTCAGTATTCAAAGGAATTTTCCTGCTCCCATCCAACATTACATGACTGGCC
TTTTGTTTGGATATTTGGATAAGTCTTTTGATGAGATGAGTGATGTATACACGAGTTTAGGGATTATTCATCTTTTTGCT
CTGTCTGGTATGCAGGTAGGCTTTTTTGTGGCACTTTTTCGTTTTATTATTTTACGTCTTGGGTTACGGCGAGATTATGT
GGATATACTGCAAATCCCGTTTTCACTTGTATATGCTGGCTTGACAGGCTTTTCGGTATCAGTTGTTCGGAGCCTTGTTC
AGTCTGCTTTTGCAAATCTTGGCATAAAAAAATTAGATAATCTTGCCTATACTTTAATGACCCTTTTTATTTTGATGCCA
AATTTTCTACTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATCCTGAGTTTTATTGATTTCGATGAGCTTAG
TCATTATCGAAAAATCCTTACAGAATGTTTGGCGATTTCGCTGGGAAGTTTACCGGTTTTGCTATATTTCTTCTCAGTAT
TTCAACCCTTGTCGCTGCTTTTAACAGCTATTTTTTCACTGGCTTTTGATACGCTTATCTTACCTGTTTTGACCTTTGTT
TTTCTTTTATCACCTCTGGTTAAAATTACCGCGTTAAATCCATTTTTTGTTTTTCTAGAAACTATCATCAAATTTAGCAA
GTCGCTGGTTGGTACCCCACTCGTTTTTGGCAGACCAAGTCTAGGAATTTTGTTGTTATTACTTTTGACAATAGGGCTTC
TCTATGACTGTTATCAACGTAAAAAAGTGGCCATTTTCCTTCTTAGCTTAATAGCTCTGCTATTTTTCCAAATCAAGCAT
CCGCTGGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAAGGGCATACGCT
GTTAATTGATGTCGGAGGAAAAGTGAGTTTTAGTGAGAAAAAATCGTGGCAAAAGCGCTTAGCTGATAGCAATGCTGAGC
GGACACTGATTCCTTATCTGAAAAGTCGAGGAATTGGTAAAATTGACCAGTTGGTTTTGACGCACACGGATACTGACCAT
ATGGGTGATATGCTGGAAGTTGCAAAAGAGCTGAAAATTGGTCAAGTCCTGGTGAGTCCAGGAAGTCTCACAAAGCCAGA
TTTTGTGGTTAAACTTCGACAAATGAAGACGCCAGTTCGCGCAGTTTTTGCAGGAGATAACTTGCCAATTATGGGAAGTC
ACTTGCAGGTGCTCTATCCAATTGAAGTTGGTGATGGTTCTAATAATGATTCGGTGGTGTTATATGGCAAGCTTTTAGGT
AAAAATTTTTTGTTTACAGGAGATTTGGAAGAAGAGGGCGAGCAACAGATGATAGCAACTTATCCCAATCTGCCAGTTGA
TGTTTTAAAAGCAGGACACCATGGTTCAAAAGGTTCATCAAGCCCAGAATTTCTAGAGCATATTTCACCGCAAGTTGTTC
TGATTTCCGCAGGACAAAATAACCGCTACAAGCATCCTCATCAAGAAACGCTTGAACGCTTTCAAGCACAAAACATGACT
ATTTACCGTACTGATGAACAAGGTGCTATCCGCTTTAGAGGGCTGAAAACTTGGCACATTGAAACAGTGAGGTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-174)

• Competence protein (Competence) (214-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-690)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	50.674	99.731	0.505
comEC/celB	Streptococcus mitis SK321	50.27	99.731	0.501
comEC/celB	Streptococcus pneumoniae TIGR4	49.798	99.866	0.497
comEC/celB	Streptococcus pneumoniae Rx1	49.394	99.866	0.493
comEC/celB	Streptococcus pneumoniae D39	49.394	99.866	0.493
comEC/celB	Streptococcus pneumoniae R6	49.394	99.866	0.493
comEC	Lactococcus lactis subsp. cremoris KW2	46.729	100	0.47