Detailed information NTG0516104

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: I6H76_RS00175
• Genome accession: NZ_CP065994
• Coordinates: 30489..31718 (+)
• Length: 409 a.a.
• NCBI ID: WP_006531277.1
• Uniprot ID: A0A380KPV6
• Organism: Streptococcus infantarius strain FDAARGOS_1019
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 25489..36718

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H76_RS00155 (I6H76_00155)	-	26079..27350 (-)	1272	WP_006531273.1	hydroxymethylglutaryl-CoA reductase, degradative	-
I6H76_RS00160 (I6H76_00160)	-	27340..28515 (-)	1176	WP_006531274.1	hydroxymethylglutaryl-CoA synthase	-
I6H76_RS00165 (I6H76_00165)	-	28844..29683 (+)	840	WP_006531275.1	thymidylate synthase	-
I6H76_RS00170 (I6H76_00170)	-	29766..30260 (+)	495	WP_006531276.1	dihydrofolate reductase	-
I6H76_RS00175 (I6H76_00175)	clpX	30489..31718 (+)	1230	WP_006531277.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
I6H76_RS00180 (I6H76_00180)	yihA	31729..32322 (+)	594	WP_043878280.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
I6H76_RS00185 (I6H76_00185)	-	32459..33835 (+)	1377	WP_006531279.1	amino acid permease	-
I6H76_RS00190 (I6H76_00190)	mmuM	33846..34790 (+)	945	WP_006531280.1	homocysteine S-methyltransferase	-
I6H76_RS00195 (I6H76_00195)	-	34824..35492 (-)	669	WP_006531281.1	YoaK family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45240.75 Da
• Isoelectric Point: 4.4880

>NTDB_id=516104 I6H76_RS00175 WP_006531277.1 30489..31718(+) (clpX) [Streptococcus infantarius strain FDAARGOS_1019]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFAESRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTTDDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAVANKAIERKTGARGLRSIIEETMMDIMFEIPSREEVTKVRITKDAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=516104 I6H76_RS00175 WP_006531277.1 30489..31718(+) (clpX) [Streptococcus infantarius strain FDAARGOS_1019]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATCAT
TGCCGGAAATAACGTATTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAGATTATTAAAGAGGAGTTAGCAGAAGAAG
TTCTCGCAGATTTGGCTGAAGTTCCAAAACCAAAAGAATTATTAGCAACCCTCGATGAATATGTTGTCGGTCAAGAACGC
GCTAAACGTGCCCTCGCAGTGGCTGTATATAACCACTACAAACGTGTTTCATTTGCCGAAAGTCGTGATGAAGAAGATGT
TGAATTACAAAAATCTAATATCCTATTAATCGGACCAACTGGTTCAGGGAAAACTTTCCTTGCCCAAACCCTAGCTAAAA
GTTTGAACGTTCCATTTGCAATTGCTGATGCGACATCATTGACGGAGGCTGGCTATGTTGGTGAAGATGTTGAAAACATT
CTTTTAAAATTAATTCAAGCAGCTGACTTCAATATTGAACGCGCAGAACGTGGTATTATTTATGTCGATGAAATTGATAA
AATTGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTCCAACAAGCTCTCCTTAAAATTA
TTGAAGGAACAGTAGCAAGCGTTCCACCACAAGGTGGTCGTAAACACCCTAACCAAGAAATGATTCAAATCAATACTAAG
AACATTCTTTTCATCGTTGGTGGTGCTTTTGATGGTATCGAAGACATTGTTAAACAACGTCTTGGTGAAAAAGTTATTGG
TTTTGGACAAAATAACCGTAAGATTGATGAAGATGCTTCTTATATGCAAGAAATCATCTCAGAAGATATTCAAAAATTCG
GTTTGATTCCAGAATTTATCGGACGCTTACCTGTTGTCGCAGCTCTTGAACAATTGACTACAGATGATTTGGTGCGAATC
TTGACAGAACCTCGTAATGCCTTGGTAAAACAATATCAAACTTTATTGTCTTATGATGGTGTTGAATTGGAATTTGATGA
AGATGCCCTTCAAGCTGTCGCAAACAAAGCTATTGAACGTAAAACAGGTGCGCGTGGTTTGCGCTCTATTATTGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCAAGTCGTGAAGAAGTCACTAAAGTCCGTATCACAAAAGATGCTGTTGAAGGC
AAAGATAAACCAATTTTAGAGATTGCCTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

3D structure

• AlphaFold DB: A0A380KPV6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575