Detailed information NTG0515866

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6H71_RS07115
• Genome accession: NZ_CP065980
• Coordinates: 1517764..1518807 (+)
• Length: 347 a.a.
• NCBI ID: WP_103207603.1
• Uniprot ID: A0A2K3ZIM8
• Organism: Staphylococcus felis strain FDAARGOS_1014
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1512764..1523807

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H71_RS07090 (I6H71_07090)	-	1513908..1514633 (+)	726	WP_103207595.1	type 1 glutamine amidotransferase	-
I6H71_RS07095 (I6H71_07095)	-	1514713..1515711 (-)	999	WP_103207596.1	FUSC family protein	-
I6H71_RS07100 (I6H71_07100)	map	1515808..1516569 (+)	762	WP_103207598.1	type I methionyl aminopeptidase	-
I6H71_RS07105 (I6H71_07105)	-	1516664..1517053 (+)	390	WP_103207599.1	hypothetical protein	-
I6H71_RS07110 (I6H71_07110)	liaF	1517066..1517767 (+)	702	WP_103207601.1	cell wall-active antibiotics response protein LiaF	-
I6H71_RS07115 (I6H71_07115)	vraS	1517764..1518807 (+)	1044	WP_103207603.1	sensor histidine kinase	Regulator
I6H71_RS07120 (I6H71_07120)	vraR	1518797..1519426 (+)	630	WP_103207605.1	response regulator	Regulator
I6H71_RS07125 (I6H71_07125)	-	1519513..1520085 (-)	573	WP_103207607.1	beta-class carbonic anhydrase	-
I6H71_RS07130 (I6H71_07130)	-	1520116..1521339 (-)	1224	WP_103207609.1	YihY/virulence factor BrkB family protein	-
I6H71_RS07135 (I6H71_07135)	-	1521702..1521989 (-)	288	WP_103207611.1	YtxH domain-containing protein	-
I6H71_RS07140 (I6H71_07140)	-	1521991..1522455 (-)	465	WP_103207612.1	low molecular weight protein-tyrosine-phosphatase	-
I6H71_RS07145 (I6H71_07145)	-	1522590..1522799 (+)	210	WP_262633092.1	DUF1128 domain-containing protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40184.49 Da
• Isoelectric Point: 5.1680

>NTDB_id=515866 I6H71_RS07115 WP_103207603.1 1517764..1518807(+) (vraS) [Staphylococcus felis strain FDAARGOS_1014]
MNHYVRTIGSMLILVYSMFTAFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLIVIFLCIIVGSVIAYKINQQNDWLQQ
QIERAFEGETVGVNDQQLELYNETLEIYRSLVPLNQELHKMRIKTQNLTNESYNLNDIKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETNLNPPLDQQIPTLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIRSLVTELQKKVPMKVIQEI
DEFDVPKGIEDHLFRITQEAISNTLRHAKGEQVTVELLKREDYLLLRIQDDGIGFNVDDKIEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEESHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=515866 I6H71_RS07115 WP_103207603.1 1517764..1518807(+) (vraS) [Staphylococcus felis strain FDAARGOS_1014]
ATGAATCACTATGTCAGAACGATTGGATCAATGCTCATACTAGTTTACAGTATGTTTACAGCTTTCTTTTTTATCGATAA
AGTTTTTGTGAATATCATATTTTTTCAAGGTATGTTTTACACTCAAATCTTCGGTATTCCTGTATTTTTATTTCTTAACT
TAATTGTCATTTTTTTGTGTATTATTGTGGGTAGTGTAATAGCGTATAAGATTAATCAACAAAATGATTGGTTACAACAA
CAGATTGAGCGTGCATTTGAAGGTGAAACAGTCGGTGTTAACGATCAGCAACTAGAGCTGTATAATGAAACATTAGAGAT
TTACCGTTCATTGGTACCGCTCAATCAAGAATTACATAAAATGCGAATTAAAACTCAAAATTTGACAAATGAATCTTATA
ACTTAAATGATATAAAAGTAAAAAAAATAATTGAAGATGAACGTCAACGGTTAGCTAGAGAGCTTCACGATAGCGTTTCG
CAGCAATTGTTTGCAGCTAGTATGATGTTATCAGCTATTAAAGAAACAAACTTAAATCCACCACTTGATCAACAGATACC
AACACTTGAAAAAATGATTCAAGACTCACAACTTGAAATGAGAGCATTATTATTACACCTACGTCCAATAGGTTTGAAGG
ATAAATCATTAGGTGAAGGCATACGATCGTTAGTGACTGAATTACAAAAGAAAGTACCTATGAAAGTTATACAAGAAATT
GATGAGTTTGATGTTCCAAAGGGTATAGAAGATCACTTATTTAGAATCACACAAGAGGCAATCTCCAATACGTTACGTCA
TGCTAAGGGTGAACAAGTGACGGTTGAATTGTTAAAAAGAGAAGACTATTTATTATTGCGTATTCAAGATGATGGTATCG
GCTTTAATGTGGACGATAAAATTGAACAAAGTTATGGTTTGAAAAATATGCGTGAAAGAGCAATTGAAATTGGTGCAACT
TTTCATATCGTCTCTTTGCCTGATGCAGGAACACGTATCGAGGTTAAAGCACCATTAGAAAAGGAGGAAAGTCATGACAA
TTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2K3ZIM8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	82.997	100	0.83