Detailed information NTG0515585

Bioinformatically predicted

Overview

• Name: pptB
• Type: Regulator
• Locus tag: KZB15_RS02290
• Genome accession: NZ_CP079922
• Coordinates: 468966..470015 (+)
• Length: 349 a.a.
• NCBI ID: WP_000653770.1
• Uniprot ID: Q8DQW6
• Organism: Streptococcus pneumoniae strain R36A
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 463966..475015

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KZB15_RS02265 (KZB15_02280)	-	465252..465608 (+)	357	WP_000114427.1	hypothetical protein	-
KZB15_RS02270 (KZB15_02285)	dnaJ	466010..467128 (+)	1119	WP_001066302.1	molecular chaperone DnaJ	-
KZB15_RS02275 (KZB15_02290)	-	467463..467750 (-)	288	WP_000777760.1	hypothetical protein	-
KZB15_RS02280 (KZB15_02295)	-	467760..468170 (-)	411	WP_001278301.1	HIT family protein	-
KZB15_RS02285 (KZB15_02300)	pptA	468238..468969 (+)	732	WP_000889919.1	ABC transporter ATP-binding protein	Regulator
KZB15_RS02290 (KZB15_02305)	pptB	468966..470015 (+)	1050	WP_000653770.1	ABC transporter permease	Regulator
KZB15_RS02295 (KZB15_02310)	-	470183..470512 (-)	330	WP_000132569.1	hypothetical protein	-
KZB15_RS02300 (KZB15_02315)	-	470788..471126 (+)	339	WP_000682124.1	LytTR family DNA-binding domain-containing protein	-
KZB15_RS02305 (KZB15_02320)	comE/blpR	471131..471868 (+)	738	WP_001219139.1	response regulator transcription factor	Regulator
KZB15_RS02310 (KZB15_02325)	-	471882..473222 (+)	1341	WP_001017622.1	sensor histidine kinase	-
KZB15_RS02315 (KZB15_02330)	blpC	473264..473419 (-)	156	WP_000358817.1	quorum-sensing system pheromone BlpC	-
KZB15_RS02320 (KZB15_02335)	-	473476..474837 (-)	1362	Protein_465	bacteriocin secretion accessory protein	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 40556.62 Da
• Isoelectric Point: 10.0008

>NTDB_id=515585 KZB15_RS02290 WP_000653770.1 468966..470015(+) (pptB) [Streptococcus pneumoniae strain R36A]
MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYSQLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEA
PDKLFLLVGEEEIKLHLKRQTGISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNLYLRSYLRNGDLFAISLRLLLLS
VLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFDYQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQE
KLALLALLGAGLVLLVLYLPYQVKRQMQD

Nucleotide

• Length: 1050 bp

>NTDB_id=515585 KZB15_RS02290 WP_000653770.1 468966..470015(+) (pptB) [Streptococcus pneumoniae strain R36A]
ATGAAAGACTTGTTTTTAAAGAGAAAGCAGGCCTTTCGTAAGGAGTGTCTTGGTTATCTGCGCTATGTGCTCAATGACCA
CTTTGTCTTGTTCCTGCTTGTCCTGTTGGGCTTTCTAGCCTACCAGTACAGTCAACTCTTACAACATTTTCCTGAAAATC
ATTGGCCTATCCTTTTGTTTGTAGGAATTACGTCTGTTTTACTCTTACTTTGGGGAGGAATTGCCACCTATATGGAGGCT
CCAGACAAGCTCTTTCTCTTAGTTGGAGAAGAGGAAATCAAGCTCCATCTCAAGCGTCAAACTGGCATTTCCCTAGTCTT
TTGGCTCTTTGTACAGACCCTTTTCTTGCTGTTATTTGCGCCTTTATTTTTAGCAATGGGTTATGGCTTGCCAGTTTTTC
TGCTCTATGTGCTTTTATTGGGGGTAGGAAAATATTTCCACTTTCGTCAAAAGGCCAGCAAATTTTTTACTGAAACTGGA
CTGGACTGGGACTATGTTATTTCTCAAGAAAGCAAGCGTAAGCAAGTCTTGCTTCGTTTCTTTGCCCTCTTTACGCAGGT
CAAGGGAATTTCAAACAGCGTTAAGCGTCGTGCCTATCTGGACTTTATCTTAAAGGCTGTTCAGAAGGTGCCTGGGAAGA
TTTGGCAAAATCTCTATCTGCGTTCTTATCTGCGAAATGGCGACCTCTTTGCTATCAGTCTTCGTCTTCTATTACTTTCC
GTACTGGCGCAGGTTTTTATCGAGCAAGCTTGGATTGCGACAGCAGTGGTAGTTCTCTTTAACTACCTCTTGCTCTTCCA
GTTGCTGGCCCTCTATCATGCCTTTGACTACCAGTATTTGACCCAACTCTTTCCGCTGGACAAGGGGCAAAAGGAAAAAG
GCTTACAGGAGGTAGTTCGAGGATTGACCAGTTTTGTTTTACTTGTGGAATTAGTTGTTGGGTTGATTACCTTCCAAGAA
AAACTGGCCCTTCTAGCCTTACTAGGAGCTGGTTTGGTTTTACTAGTCTTGTATTTGCCTTATCAGGTAAAACGTCAGAT
GCAGGACTAA

Domains

Predicted by InterProScan.

• Bacterial ABC transporter protein EcsB (EcsB) (2-156)

• Bacterial ABC transporter protein EcsB (EcsB) (158-331)

3D structure

• AlphaFold DB: Q8DQW6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptB	Streptococcus salivarius strain HSISS4	47.429	100	0.476
pptB	Streptococcus thermophilus LMD-9	46.571	100	0.467