Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   KZH40_RS01445 Genome accession   NZ_CP079921
Coordinates   307674..309506 (+) Length   610 a.a.
NCBI ID   WP_005600343.1    Uniprot ID   -
Organism   Actinobacillus pleuropneumoniae strain P1875     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 302674..314506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZH40_RS01420 (KZH40_01440) - 302684..303580 (-) 897 WP_005596167.1 metal ABC transporter substrate-binding protein -
  KZH40_RS01425 (KZH40_01445) - 303647..303982 (-) 336 WP_043993336.1 TusE/DsrC/DsvC family sulfur relay protein -
  KZH40_RS01430 (KZH40_01450) - 304034..304699 (-) 666 WP_005596172.1 Bax inhibitor-1 family protein -
  KZH40_RS01435 (KZH40_01455) pgsA 304880..305431 (+) 552 WP_005618995.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KZH40_RS01440 (KZH40_01460) - 305551..307521 (+) 1971 WP_005596175.1 TonB-dependent receptor domain-containing protein -
  KZH40_RS01445 (KZH40_01465) uvrC 307674..309506 (+) 1833 WP_005600343.1 excinuclease ABC subunit UvrC Machinery gene
  KZH40_RS01450 (KZH40_01470) - 309575..310327 (+) 753 WP_005600345.1 TatD family hydrolase -
  KZH40_RS01455 (KZH40_01475) rep 310362..312380 (-) 2019 WP_005600347.1 DNA helicase Rep -
  KZH40_RS01460 (KZH40_01480) potA 312714..313829 (+) 1116 WP_005600350.1 spermidine/putrescine ABC transporter ATP-binding protein PotA -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 69142.91 Da        Isoelectric Point: 8.9083

>NTDB_id=515518 KZH40_RS01445 WP_005600343.1 307674..309506(+) (uvrC) [Actinobacillus pleuropneumoniae strain P1875]
MFDAKAFLADVPHLPGVYRMYDAKNTIIYVGKAKDLKKRLSSYFRSQLASKKTEALVANIHHIETTITHSETEALLLEHN
YIKENQPKYNVLLRDDKSYPYILLTKHQHPRITSFRGSKKVAGEYFGPYPNAGAVRETLNLLQKLFPIRQCEDSYYKNRS
RPCLQYQIGRCLAPCVEGYYSQAEYDNQVNLVRLFLQGKDGQVVEHLVQKMENAAQDLDFEAAARFRDQIQSVRAVQEKQ
FVSNERLDDLDIISIAYQHGIACVHILFVRHGKVLGNRSYFPKVPNNTDLSELADTFVGQFYLQMNQHRTIPNQIIIDQS
LSEVTALANVLSEQAGHKVSIADKNIRGDKSRYLALAKTNAEAALTLQLKQDTHIRQRYDSLKTLLNLAEIKRMECFDIS
HTMGNQTVASCVVFDENGPLKSDYRRFNIEGITGGDDYAAIEQALLKRYDRNLEEEKIPDIIFIDGGKGQLNRALETFTS
LNVSWDKRKPLLVGVAKGVERKAGLETLLISKWDKEIHLPPDSPALHLIQHIRDESHNHAITGHRKKRQKAFTESGLESI
AGVGAKRRQALLKYLGGMQGVKAATLEEIQSVPGISKQLAEVIFDTLQHS

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=515518 KZH40_RS01445 WP_005600343.1 307674..309506(+) (uvrC) [Actinobacillus pleuropneumoniae strain P1875]
ATGTTTGATGCCAAAGCCTTTCTTGCCGATGTTCCTCATCTTCCCGGTGTTTATCGTATGTATGATGCGAAAAATACTAT
TATCTATGTCGGTAAAGCCAAAGATCTTAAAAAACGCTTATCCAGTTATTTTCGTAGCCAACTCGCCAGTAAGAAAACCG
AGGCGTTAGTCGCTAACATTCATCATATCGAAACCACGATTACCCATTCGGAAACGGAAGCGTTACTACTTGAACATAAT
TACATTAAAGAGAATCAGCCGAAGTACAACGTGCTTTTGCGTGATGATAAATCCTATCCGTATATTTTACTCACAAAGCA
TCAACATCCCCGAATTACTTCGTTTCGTGGTAGTAAAAAAGTTGCCGGTGAATATTTTGGCCCGTATCCGAATGCAGGTG
CAGTGCGTGAAACGCTAAACTTGCTGCAAAAACTGTTTCCGATTCGCCAATGTGAAGACAGCTACTATAAAAATCGTTCT
CGCCCTTGTTTGCAATACCAAATCGGGCGTTGTCTTGCCCCTTGTGTAGAAGGTTATTACTCACAAGCGGAATATGATAA
CCAAGTAAATTTAGTCCGTTTGTTTTTACAAGGTAAAGACGGACAAGTGGTTGAGCATTTGGTACAAAAAATGGAAAACG
CTGCGCAAGATCTGGATTTTGAAGCGGCGGCTCGTTTTCGCGATCAGATCCAATCGGTACGAGCGGTGCAAGAAAAACAA
TTTGTCTCTAACGAACGTTTGGATGATTTGGATATTATTTCGATCGCTTATCAACACGGTATTGCTTGCGTACATATTTT
ATTTGTGCGTCACGGTAAGGTATTGGGTAATCGTTCCTATTTTCCTAAAGTGCCGAACAATACCGATTTAAGCGAGTTGG
CGGATACCTTTGTCGGTCAGTTTTATTTACAAATGAACCAACATCGCACGATACCGAATCAAATTATTATCGATCAGTCG
TTAAGTGAAGTGACTGCATTAGCTAATGTGCTGTCCGAACAAGCGGGGCATAAAGTCAGTATTGCCGATAAAAATATTCG
TGGCGATAAAAGCCGCTATTTGGCATTGGCAAAAACTAACGCGGAAGCCGCTCTTACTTTACAACTTAAACAAGATACGC
ATATTCGCCAGCGTTATGATTCGCTTAAAACATTACTCAATTTAGCGGAAATCAAGCGAATGGAGTGTTTCGATATTTCT
CACACAATGGGTAATCAAACGGTCGCTTCTTGTGTCGTGTTTGATGAAAACGGGCCGCTAAAATCGGATTACCGCCGTTT
TAATATTGAAGGTATTACCGGTGGTGATGACTATGCGGCAATAGAACAAGCCTTATTAAAACGTTATGACCGCAATTTAG
AAGAAGAAAAAATTCCGGATATTATTTTTATTGATGGTGGGAAAGGTCAGCTGAATCGAGCGTTGGAAACCTTTACTTCG
TTAAATGTCAGTTGGGATAAGCGCAAACCGTTGTTAGTTGGTGTGGCGAAAGGAGTAGAGCGAAAAGCCGGTTTAGAAAC
TTTATTGATCAGCAAATGGGATAAGGAAATTCACTTACCGCCGGACAGTCCCGCACTACATTTGATTCAACATATTCGTG
ACGAATCGCATAATCACGCAATAACCGGACACCGTAAAAAGCGCCAAAAAGCCTTTACGGAAAGTGGCTTAGAATCAATC
GCCGGTGTTGGAGCAAAACGTCGCCAAGCGTTACTGAAATACCTCGGCGGAATGCAGGGCGTGAAAGCCGCAACTTTAGA
AGAAATTCAATCCGTACCCGGTATTTCAAAGCAACTTGCCGAAGTGATTTTTGATACGTTACAGCATAGCTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(202-235)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-541)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.11

99.836

0.37
  uvrC Streptococcus pneumoniae R6

36.782

99.836

0.367
  uvrC Streptococcus pneumoniae D39

36.782

99.836

0.367