Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KYX59_RS07465 Genome accession   NZ_CP079780
Coordinates   1093192..1093848 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain BL12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1088192..1098848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KYX59_RS07435 (KYX59_07375) - 1089325..1090064 (+) 740 Protein_1088 hypothetical protein -
  KYX59_RS07455 (KYX59_07395) pgsA 1090758..1091306 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KYX59_RS07460 (KYX59_07400) uvrC 1091363..1093195 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  KYX59_RS07465 (KYX59_07405) letA 1093192..1093848 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KYX59_RS24565 - 1093990..1094061 (+) 72 Protein_1092 transcriptional regulator -
  KYX59_RS07470 (KYX59_07410) yecU 1094144..1094320 (+) 177 WP_001307856.1 protein YecU -
  KYX59_RS07475 (KYX59_07415) yecF 1094307..1094531 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  KYX59_RS07480 (KYX59_07420) sdiA 1094598..1095320 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  KYX59_RS07485 (KYX59_07425) tcyN 1095550..1096302 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KYX59_RS07490 (KYX59_07430) tcyL 1096299..1096967 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  KYX59_RS07495 (KYX59_07435) dcyD 1096982..1097968 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=515441 KYX59_RS07465 WP_000611328.1 1093192..1093848(-) (letA) [Escherichia coli strain BL12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=515441 KYX59_RS07465 WP_000611328.1 1093192..1093848(-) (letA) [Escherichia coli strain BL12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482