Detailed information NTG0515372

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: JAN99_RS05750
• Genome accession: NZ_CP065927
• Coordinates: 1151163..1152392 (-)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm9ST603
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1146163..1157392

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JAN99_RS05730 (JAN99_05725)	rpiA	1146448..1147131 (-)	684	WP_020905094.1	ribose-5-phosphate isomerase RpiA	-
JAN99_RS05735 (JAN99_05730)	-	1147509..1149605 (+)	2097	WP_111693129.1	ATP-dependent Clp protease ATP-binding subunit	-
JAN99_RS05740 (JAN99_05735)	-	1149663..1150406 (-)	744	WP_002984942.1	hypothetical protein	-
JAN99_RS05745 (JAN99_05740)	yihA	1150554..1151153 (-)	600	WP_111693128.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
JAN99_RS05750 (JAN99_05745)	clpX	1151163..1152392 (-)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
JAN99_RS05755 (JAN99_05750)	-	1152712..1153209 (-)	498	WP_136116077.1	dihydrofolate reductase	-
JAN99_RS05760 (JAN99_05755)	-	1153289..1154128 (-)	840	WP_011017679.1	thymidylate synthase	-
JAN99_RS05765 (JAN99_05760)	-	1154337..1155512 (+)	1176	WP_032464957.1	hydroxymethylglutaryl-CoA synthase	-
JAN99_RS05770 (JAN99_05765)	-	1155499..1156776 (+)	1278	WP_002984963.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=515372 JAN99_RS05750 WP_009880296.1 1151163..1152392(-) (clpX) [Streptococcus pyogenes strain emm9ST603]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=515372 JAN99_RS05750 WP_009880296.1 1151163..1152392(-) (clpX) [Streptococcus pyogenes strain emm9ST603]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCTAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCTCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTCAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575