Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KX927_RS05775 Genome accession   NZ_CP079767
Coordinates   713578..714234 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain SF10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 708578..719234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX927_RS05745 (KX927_05695) dcyD 709457..710443 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KX927_RS05750 (KX927_05700) tcyL 710458..711126 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KX927_RS05755 (KX927_05705) tcyN 711123..711875 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KX927_RS05760 (KX927_05710) sdiA 712105..712827 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  KX927_RS05765 (KX927_05715) yecF 712895..713119 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KX927_RS05770 (KX927_05720) yecU 713106..713282 (-) 177 WP_000590344.1 protein YecU -
  KX927_RS25935 - 713320..713436 (-) 117 WP_001302039.1 hypothetical protein -
  KX927_RS05775 (KX927_05725) letA 713578..714234 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KX927_RS05780 (KX927_05730) uvrC 714231..716063 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  KX927_RS05785 (KX927_05735) pgsA 716120..716668 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KX927_RS05805 (KX927_05755) - 717363..718103 (-) 741 WP_206054697.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=515200 KX927_RS05775 WP_000611328.1 713578..714234(+) (letA) [Escherichia coli strain SF10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=515200 KX927_RS05775 WP_000611328.1 713578..714234(+) (letA) [Escherichia coli strain SF10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482