Detailed information NTG0514963

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: IAU57_RS25495
• Genome accession: NZ_CP065848
• Coordinates: 5419322..5421547 (-)
• Length: 741 a.a.
• NCBI ID: WP_003113988.1
• Uniprot ID: Q9HZM0
• Organism: Pseudomonas aeruginosa strain CMC-097
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 5414322..5426547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IAU57_RS25460 (IAU57_25460)	murB	5414712..5415731 (-)	1020	WP_017149173.1	UDP-N-acetylmuramate dehydrogenase	-
IAU57_RS25465 (IAU57_25465)	-	5415728..5416192 (-)	465	WP_003106924.1	low molecular weight protein-tyrosine-phosphatase	-
IAU57_RS25470 (IAU57_25470)	kdsB	5416192..5416956 (-)	765	WP_003106922.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
IAU57_RS25475 (IAU57_25475)	-	5416956..5417141 (-)	186	WP_003091157.1	Trm112 family protein	-
IAU57_RS25480 (IAU57_25480)	lpxK	5417179..5418177 (-)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
IAU57_RS25485 (IAU57_25485)	-	5418177..5418617 (-)	441	WP_003091161.1	biopolymer transporter ExbD	-
IAU57_RS25490 (IAU57_25490)	exbB	5418614..5419249 (-)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
IAU57_RS25495 (IAU57_25495)	comA	5419322..5421547 (-)	2226	WP_003113988.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
IAU57_RS25500 (IAU57_25500)	-	5421678..5422211 (+)	534	WP_003091165.1	DUF2062 domain-containing protein	-
IAU57_RS25505 (IAU57_25505)	-	5422299..5423543 (-)	1245	WP_003113987.1	lipoprotein-releasing ABC transporter permease subunit	-
IAU57_RS25510 (IAU57_25510)	lolD	5423613..5424296 (-)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
IAU57_RS25515 (IAU57_25515)	-	5424289..5425539 (-)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
IAU57_RS25520 (IAU57_25520)	-	5425642..5426241 (+)	600	WP_003105196.1	PilZ domain-containing protein	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79979.60 Da
• Isoelectric Point: 10.3506

>NTDB_id=514963 IAU57_RS25495 WP_003113988.1 5419322..5421547(-) (comA) [Pseudomonas aeruginosa strain CMC-097]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHVLLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPVWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=514963 IAU57_RS25495 WP_003113988.1 5419322..5421547(-) (comA) [Pseudomonas aeruginosa strain CMC-097]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAGCGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGGTTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGCGCCTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTGTGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCATTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGAGAGCATGTCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGTTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: Q9HZM0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.807	97.301	0.572
comA	Ralstonia pseudosolanacearum GMI1000	35.611	100	0.366