Detailed information NTG0514642

Bioinformatically predicted

Overview

• Name: uvrC
• Type: Machinery gene
• Locus tag: KX728_RS06950
• Genome accession: NZ_CP079724
• Coordinates: 1405339..1407186 (-)
• Length: 615 a.a.
• NCBI ID: WP_215804436.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain 34
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1400339..1412186

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KX728_RS06925 (KX728_06920)	-	1401375..1401662 (-)	288	WP_215804441.1	rhodanese-like domain-containing protein	-
KX728_RS06930 (KX728_06925)	-	1401659..1402249 (-)	591	WP_215804440.1	uracil-DNA glycosylase family protein	-
KX728_RS06935 (KX728_06930)	pepV	1402303..1403703 (-)	1401	WP_215804439.1	dipeptidase PepV	-
KX728_RS06940 (KX728_06935)	-	1403716..1404321 (-)	606	WP_215804438.1	nitroreductase family protein	-
KX728_RS06945 (KX728_06940)	-	1404495..1405349 (-)	855	WP_215804437.1	metallophosphoesterase	-
KX728_RS06950 (KX728_06945)	uvrC	1405339..1407186 (-)	1848	WP_215804436.1	excinuclease ABC subunit UvrC	Machinery gene
KX728_RS06955 (KX728_06950)	-	1407287..1407988 (-)	702	WP_215804435.1	M57 family metalloprotease	-
KX728_RS06960 (KX728_06955)	-	1408093..1408872 (-)	780	WP_215804434.1	alpha/beta hydrolase family protein	-
KX728_RS06965 (KX728_06960)	-	1408941..1410602 (-)	1662	WP_215804433.1	ribonuclease J	-
KX728_RS06970 (KX728_06965)	-	1411113..1411760 (-)	648	WP_215804432.1	CHAP domain-containing protein	-

Sequence

Protein

• Length: 615 a.a.
• Molecular weight: 70517.09 Da
• Isoelectric Point: 8.9904

>NTDB_id=514642 KX728_RS06950 WP_215804436.1 1405339..1407186(-) (uvrC) [Streptococcus oralis strain 34]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKGKMAVAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYYNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGHLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQRDGLTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQRKLTPQEAVKLAQVAEERVDYQTEGEHHEP

Nucleotide

• Length: 1848 bp

>NTDB_id=514642 KX728_RS06950 WP_215804436.1 1405339..1407186(-) (uvrC) [Streptococcus oralis strain 34]
ATGAATAACTTGATCAAATCAAAACTGGAGCTCTTGCCGACCAGCCCCGGTTGTTACATTCACAAAGATAAAAACGGCAC
TATTATCTATGTAGGAAAGGCAAAAAATCTGCGCAATCGCGTGCGGTCCTACTTTCGTGGCAGTCACGATACCAAGACAG
AAGCTCTGGTATCTGAAATTGTAGATTTTGAATTTATCGTTACCGAGTCTAATATTGAGGCCCTCCTTCTGGAAATCAAC
CTTATCAAGGAAAATAAGCCCAAGTACAATATCATGCTCAAGGATGATAAGTCCTATCCCTTTATCAAAATCACCAATGA
GCGCTATCCGCGGCTTATTATTACTCGTCAGGTCAAAAAGGATGGAGGGCTTTATTTTGGTCCTTATCCAGATGTGGGGG
CGGCCAATGAAATCAAGCGGCTACTGGATCGGATTTTCCCTTTTCGTAAGTGTACTAATCCGCCGTCTAAGGTCTGTTTC
TATTACCATATCGGTCAATGTATGGCCCACACCATCTGTAAAAAAGATGAGGCCTACTTCAAGTCCATGGCTCAGGAGGT
TTCTGATTTCCTAAAAGGACAGGATGACAAAATCATCGATGATCTCAAGGGTAAAATGGCAGTGGCAGCCCAAAGTATGG
AGTTTGAACGGGCGGCGGAATACCGTGATTTGATTCAGGCCATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCCAAG
GACCTCCAAAACCGTGATGTCTTTGGCTACTATGTGGACAAGGGCTGGATGTGTGTACAGGTTTTCTTTGTTCGTCAAGG
CAAGCTCATCGAGCGCGACGTCAACCTCTTCCCTTACTACAATGATCCGGACGAGGACTTTCTAACCTATGTGGGACAAT
TTTATCAAGAAAAATCTCACCTGGTTCCCAATGAAGTATTGATTCCACAGGATATTGACGAAGAAGCAGTCAAGGCCTTG
GTGGATACCAAGATTCTCAAACCCCAGCGTGGAGAGAAAAAACAGCTGGTCAATCTAGCCATCAAAAATGCCCGTGTCAG
TCTGGAGCAGAAGTTCAATCTGCTAGAAAAATCTGTCGAAAAGACCCAAGGAGCTATTGAAAATCTAGGACACTTGCTTC
AAATACCAACTCCGGTTCGCATTGAGTCCTTCGACAACTCCAATATCATGGGAACTAGCCCTGTTTCGGCTATGGTGGTC
TTTGTCAACGGTAAACCGAGTAAGAAGGATTACCGTAAGTACAAGATAAAAACGGTTGTGGGTCCAGACGATTATGCGAG
TATGCGAGAAGTCATTCGCAGACGTTATGGTCGAGTACAACGAGACGGTTTGACCCCACCAGATTTGATTGTGATTGATG
GGGGACAAGGGCAAGTCAATATTGCTAAGCAGGTCATCCAAGAGGAGCTGGGCTTGGATATTCCCATTGCTGGGCTGCAA
AAGAATGACAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTGGAAGTGGTGGAGTTGTCTCGCAATTCTCAAGA
ATTCTTTCTCCTCCAACGCATCCAGGATGAGGTGCACCGTTTTGCCATCACCTTCCACCGTCAACTGCGCTCGAAAAATT
CTTTTTCTTCACAACTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTCATGAAGCATTTCAAGTCTTTG
ACTAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGAGTACCAAGAGCAGTCGCAGAAGCTGTGCAAAGAAA
GTTGACCCCGCAGGAAGCAGTGAAACTGGCTCAAGTTGCGGAAGAAAGAGTAGATTATCAAACAGAAGGAGAACATCATG
AACCATAA

Domains

Predicted by InterProScan.

• UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom) (373-523)

• UvrB/uvrC motif (UVR) (196-228)

• GIY-YIG catalytic domain (GIY-YIG) (17-90)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrC	Streptococcus pneumoniae TIGR4	97.398	100	0.974
uvrC	Streptococcus pneumoniae R6	97.073	100	0.971
uvrC	Streptococcus pneumoniae D39	97.073	100	0.971