Detailed information
Bioinformatically predicted
Overview
| Name | comR | Type | Regulator |
| Locus tag | SSUST1_RS00365 | Genome accession | NC_017950 |
| Coordinates | 62902..63801 (+) | Length | 299 a.a. |
| NCBI ID | WP_014735243.1 | Uniprot ID | - |
| Organism | Streptococcus suis ST1 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 13614..61952 | 62902..63801 | flank | 950 |
| IScluster/Tn | 64227..66921 | 62902..63801 | flank | 426 |
Gene organization within MGE regions
Location: 13614..66921
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SSUST1_RS00075 (SSUST1_0016) | ftsH | 13614..15584 (+) | 1971 | WP_014735204.1 | ATP-dependent zinc metalloprotease FtsH | - |
| SSUST1_RS00080 (SSUST1_0017) | - | 15940..16409 (+) | 470 | Protein_15 | sigma-70 family RNA polymerase sigma factor | - |
| SSUST1_RS00185 (SSUST1_0020) | mreC | 23704..24540 (+) | 837 | WP_014735206.1 | rod shape-determining protein MreC | - |
| SSUST1_RS00190 (SSUST1_0021) | mreD | 24530..25045 (+) | 516 | WP_002935339.1 | rod shape-determining protein MreD | - |
| SSUST1_RS00195 (SSUST1_0022) | pcsB | 25130..26386 (+) | 1257 | WP_014735207.1 | peptidoglycan hydrolase PcsB | - |
| SSUST1_RS00200 (SSUST1_0023) | - | 26451..27677 (-) | 1227 | WP_200857798.1 | ISL3 family transposase | - |
| SSUST1_RS00205 (SSUST1_0024) | - | 27911..28879 (+) | 969 | WP_014735209.1 | ribose-phosphate diphosphokinase | - |
| SSUST1_RS00210 (SSUST1_0025) | - | 28966..30144 (+) | 1179 | WP_014735210.1 | pyridoxal phosphate-dependent aminotransferase | - |
| SSUST1_RS00215 (SSUST1_0026) | recO | 30131..30913 (+) | 783 | WP_014735211.1 | DNA repair protein RecO | - |
| SSUST1_RS00220 (SSUST1_0027) | plsX | 30910..31917 (+) | 1008 | WP_014735212.1 | phosphate acyltransferase PlsX | - |
| SSUST1_RS00225 (SSUST1_0028) | - | 31910..32158 (+) | 249 | WP_014637254.1 | phosphopantetheine-binding protein | - |
| SSUST1_RS00230 (SSUST1_0030) | tnpA | 32329..32792 (+) | 464 | Protein_25 | IS200/IS605-like element ISSsu4 family transposase | - |
| SSUST1_RS00235 (SSUST1_0031) | purC | 33031..33738 (+) | 708 | WP_014735214.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| SSUST1_RS00240 (SSUST1_0032) | - | 33751..37470 (+) | 3720 | WP_024405312.1 | phosphoribosylformylglycinamidine synthase | - |
| SSUST1_RS00245 (SSUST1_0033) | purF | 37473..38927 (+) | 1455 | WP_014735216.1 | amidophosphoribosyltransferase | - |
| SSUST1_RS00250 (SSUST1_0034) | tnpA | 39132..39645 (-) | 514 | Protein_29 | IS200/IS605 family transposase | - |
| SSUST1_RS00255 (SSUST1_0035) | purM | 39792..40811 (+) | 1020 | WP_024405246.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| SSUST1_RS00260 (SSUST1_0036) | purN | 40808..41359 (+) | 552 | WP_014735219.1 | phosphoribosylglycinamide formyltransferase | - |
| SSUST1_RS00265 (SSUST1_0037) | purH | 41369..42916 (+) | 1548 | WP_014735220.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| SSUST1_RS00270 (SSUST1_0038) | - | 43015..43866 (+) | 852 | WP_014735221.1 | hypothetical protein | - |
| SSUST1_RS00275 (SSUST1_0039) | purD | 44001..45266 (+) | 1266 | WP_014735222.1 | phosphoribosylamine--glycine ligase | - |
| SSUST1_RS00280 (SSUST1_0040) | - | 45256..45702 (+) | 447 | WP_014735223.1 | DUF523 domain-containing protein | - |
| SSUST1_RS00285 (SSUST1_0041) | purE | 45699..46187 (+) | 489 | WP_014735224.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| SSUST1_RS00290 (SSUST1_0042) | purK | 46174..47268 (+) | 1095 | WP_014735225.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
| SSUST1_RS00295 (SSUST1_0043) | - | 47283..49805 (+) | 2523 | WP_014735226.1 | DEAD/DEAH box helicase | - |
| SSUST1_RS00300 (SSUST1_0044) | purB | 50200..51492 (+) | 1293 | WP_014735227.1 | adenylosuccinate lyase | - |
| SSUST1_RS00305 (SSUST1_0045) | tnpA | 51683..52147 (+) | 465 | WP_002939996.1 | IS200/IS605-like element ISSsu4 family transposase | - |
| SSUST1_RS00310 (SSUST1_0046) | - | 52571..53395 (+) | 825 | WP_014735229.1 | ABC transporter ATP-binding protein | - |
| SSUST1_RS00315 (SSUST1_0047) | - | 53388..54131 (+) | 744 | WP_014735230.1 | ABC transporter permease | - |
| SSUST1_RS00320 (SSUST1_0049) | - | 54457..55185 (+) | 729 | WP_014735232.1 | hypothetical protein | - |
| SSUST1_RS00325 (SSUST1_0051) | - | 55342..55773 (+) | 432 | WP_234944137.1 | CPBP family intramembrane glutamic endopeptidase | - |
| SSUST1_RS00330 (SSUST1_0052) | - | 55788..56216 (+) | 429 | WP_024405339.1 | Msa family membrane protein | - |
| SSUST1_RS00335 (SSUST1_0053) | - | 56209..57081 (+) | 873 | WP_014735236.1 | ABC transporter ATP-binding protein | - |
| SSUST1_RS00340 (SSUST1_0054) | - | 57087..57861 (+) | 775 | Protein_47 | hypothetical protein | - |
| SSUST1_RS00345 (SSUST1_0056) | tnpA | 58129..58642 (+) | 514 | Protein_48 | IS200/IS605 family transposase | - |
| SSUST1_RS00350 (SSUST1_0057) | - | 58780..60381 (+) | 1602 | WP_014735239.1 | ABC transporter ATP-binding protein | - |
| SSUST1_RS11140 (SSUST1_0058) | - | 60483..60656 (+) | 174 | WP_014735240.1 | hypothetical protein | - |
| SSUST1_RS00355 (SSUST1_0059) | ruvB | 60951..61952 (+) | 1002 | WP_014735241.1 | Holliday junction branch migration DNA helicase RuvB | - |
| SSUST1_RS00360 (SSUST1_0060) | - | 62020..62655 (+) | 636 | WP_014735242.1 | HAD-IA family hydrolase | - |
| SSUST1_RS00365 (SSUST1_0061) | comR | 62902..63801 (+) | 900 | WP_014735243.1 | helix-turn-helix domain-containing protein | Regulator |
| SSUST1_RS00370 | - | 64227..65429 (+) | 1203 | Protein_54 | IS110 family transposase | - |
| SSUST1_RS00375 (SSUST1_0065) | - | 65984..66921 (-) | 938 | Protein_55 | IS4 family transposase | - |
Sequence
Protein
Download Length: 299 a.a. Molecular weight: 35453.36 Da Isoelectric Point: 4.6492
>NTDB_id=51448 SSUST1_RS00365 WP_014735243.1 62902..63801(+) (comR) [Streptococcus suis ST1]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQMNIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQMNIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ
Nucleotide
Download Length: 900 bp
>NTDB_id=51448 SSUST1_RS00365 WP_014735243.1 62902..63801(+) (comR) [Streptococcus suis ST1]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATGAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATGAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comR | Streptococcus suis P1/7 |
99.331 |
100 |
0.993 |
| comR | Streptococcus suis 05ZYH33 |
99.331 |
100 |
0.993 |
| comR | Streptococcus suis D9 |
61.462 |
100 |
0.619 |
| comR | Streptococcus mutans UA159 |
43.813 |
100 |
0.438 |
| comR | Streptococcus pyogenes MGAS315 |
37.374 |
99.331 |
0.371 |