Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   KWY62_RS02120 Genome accession   NZ_CP079193
Coordinates   418509..419150 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain ID41570     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 413509..424150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KWY62_RS02100 (KWY62_02100) - 413811..414548 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KWY62_RS02105 (KWY62_02105) pknB 414548..416200 (+) 1653 Protein_381 Stk1 family PASTA domain-containing Ser/Thr kinase -
  KWY62_RS10430 - 416327..416542 (+) 216 Protein_382 serine/threonine protein kinase -
  KWY62_RS02110 (KWY62_02110) liaF 416865..417524 (+) 660 WP_228475102.1 cell wall-active antibiotics response protein LiaF -
  KWY62_RS02115 (KWY62_02115) - 417521..418537 (+) 1017 WP_044668898.1 sensor histidine kinase -
  KWY62_RS02120 (KWY62_02120) vraR 418509..419150 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  KWY62_RS02125 (KWY62_02125) - 419200..420600 (+) 1401 WP_044668895.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  KWY62_RS02130 (KWY62_02130) - 420602..420973 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  KWY62_RS02135 (KWY62_02135) cysK 420999..421925 (-) 927 WP_044668892.1 cysteine synthase A -
  KWY62_RS02140 (KWY62_02140) - 422015..422647 (-) 633 WP_015646510.1 YigZ family protein -
  KWY62_RS02145 (KWY62_02145) comFA/cflA 422704..423996 (+) 1293 WP_044668890.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=514269 KWY62_RS02120 WP_002937025.1 418509..419150(+) (vraR) [Streptococcus suis strain ID41570]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=514269 KWY62_RS02120 WP_002937025.1 418509..419150(+) (vraR) [Streptococcus suis strain ID41570]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTCCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTGGAGGTTAAGCCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACTTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413