Detailed information NTG0514190

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: KV381_RS15675
• Genome accession: NZ_CP079114
• Coordinates: 3613244..3614368 (+)
• Length: 374 a.a.
• NCBI ID: WP_006125491.1
• Uniprot ID: A0ABT7DGV6
• Organism: Streptomyces sp. WY228
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3608244..3619368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV381_RS15660 (KV381_15660)	-	3608713..3609573 (+)	861	WP_030087851.1	hypothetical protein	-
KV381_RS15665 (KV381_15665)	-	3609618..3611525 (-)	1908	WP_218785422.1	hypothetical protein	-
KV381_RS15670 (KV381_15670)	radA/sms	3611742..3613163 (+)	1422	WP_103536762.1	DNA repair protein RadA	Machinery gene
KV381_RS15675 (KV381_15675)	disA	3613244..3614368 (+)	1125	WP_006125491.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
KV381_RS15680 (KV381_15680)	-	3614653..3615477 (-)	825	WP_234024694.1	hypothetical protein	-
KV381_RS15685 (KV381_15685)	-	3615696..3616610 (+)	915	WP_030087860.1	A/G-specific adenine glycosylase	-
KV381_RS15690 (KV381_15690)	-	3616772..3617443 (+)	672	WP_030087862.1	SigE family RNA polymerase sigma factor	-
KV381_RS15695 (KV381_15695)	-	3617572..3618255 (+)	684	WP_030625806.1	hypothetical protein	-
KV381_RS15700 (KV381_15700)	cseB	3618336..3619049 (+)	714	WP_030087866.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40412.35 Da
• Isoelectric Point: 4.9406

>NTDB_id=514190 KV381_RS15675 WP_006125491.1 3613244..3614368(+) (disA) [Streptomyces sp. WY228]
MAANDRATTPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDRTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDSLSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=514190 KV381_RS15675 WP_006125491.1 3613244..3614368(+) (disA) [Streptomyces sp. WY228]
GTGGCAGCCAACGACCGGGCGACGACGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAGGCGCTGATGCGCGCCTCGTT
GAGCGCGGTCGCGCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAATACCGGTGGCCTGATCGTGC
TGGGCATGGACAGAACCGTCGAGTCGATGTGTACCGGCGGATTCGTGCTGGACGTGGAGTTCACGGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGGGCGCTGATCCTGGACAAGGACATGACCAAGATCCTGCGGGCCGGGGTGCAGCTGGTCCC
GGACGCCTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGCTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTGTCCCGGGCCAACCAGGCGCTCGCGACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTGGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGGCTGGAGATGGTGCGGCGGATCG
CGACGGAGATCGCGGAGTACGTGGTCGAGCTCGGCACCGACGGACGGCTCCTCTCGCTCCAGCTGGACGAGCTGATCGCC
GGGGTGGAGCCGGAGCGGGAGCTGGTCGTCCGGGACTACGTCCCCGAACCGACGGCGAAACGGTCGCGCACGGTGGCCGA
GGCGCTGACCGAGCTGGACTCCCTGAGCCACACGGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGCTACAGCG
GCTCGCCGGAGACGCTGGACTCGGCGGTGTCGCCGCGGGGCTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGTGGCCTCCAGAAGCTGCTGGCGGCCAGCGTGGACGATCTCCAGACGGTGGA
CGGGGTGGGCGAGGCCCGGGCGCGGAGTGTGCGCGAGGGGCTGTCGCGGTTGGCGGAGTCGTCGATCCTGGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436