Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   I6G41_RS13710 Genome accession   NZ_CP065710
Coordinates   2736025..2737653 (+) Length   542 a.a.
NCBI ID   WP_197910908.1    Uniprot ID   -
Organism   Staphylococcus equorum strain FDAARGOS_884     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2738562..2747537 2736025..2737653 flank 909
SCCmec 2723951..2736004 2736025..2737653 flank 21


Gene organization within MGE regions


Location: 2723951..2747537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G41_RS13650 (I6G41_13650) - 2723951..2725876 (-) 1926 WP_053027547.1 heavy metal translocating P-type ATPase -
  I6G41_RS13655 (I6G41_13655) - 2726206..2726532 (-) 327 WP_031920602.1 ArsR/SmtB family transcription factor -
  I6G41_RS13660 (I6G41_13660) - 2726739..2727098 (+) 360 WP_001631039.1 hypothetical protein -
  I6G41_RS13665 (I6G41_13665) - 2727210..2727548 (-) 339 Protein_2616 recombinase family protein -
  I6G41_RS13670 (I6G41_13670) - 2727557..2727877 (+) 321 Protein_2617 hypothetical protein -
  I6G41_RS13675 (I6G41_13675) - 2727849..2728124 (+) 276 WP_119627606.1 hypothetical protein -
  I6G41_RS13680 (I6G41_13680) - 2728731..2730149 (-) 1419 WP_031920597.1 RNA-binding domain-containing protein -
  I6G41_RS13685 (I6G41_13685) - 2730296..2731834 (+) 1539 WP_031920596.1 hypothetical protein -
  I6G41_RS13690 (I6G41_13690) - 2732067..2732306 (+) 240 WP_031920595.1 hypothetical protein -
  I6G41_RS13695 (I6G41_13695) cch1 2732332..2734119 (+) 1788 WP_197910907.1 cassette chromosome replicative helicase -
  I6G41_RS13700 (I6G41_13700) - 2734188..2734463 (+) 276 WP_031920593.1 hypothetical protein -
  I6G41_RS13705 (I6G41_13705) ccrA 2734655..2736004 (+) 1350 WP_031920592.1 cassette chromosome recombinase CcrA Machinery gene
  I6G41_RS13710 (I6G41_13710) ccrB 2736025..2737653 (+) 1629 WP_197910908.1 cassette chromosome recombinase CcrB Machinery gene
  I6G41_RS13715 (I6G41_13715) - 2738128..2738466 (+) 339 WP_046465684.1 SAUGI family uracil-DNA glycosylase inhibitor -
  I6G41_RS13720 (I6G41_13720) - 2738562..2738873 (+) 312 WP_078073177.1 DUF960 family protein -
  I6G41_RS13725 (I6G41_13725) - 2738889..2739392 (+) 504 WP_078073176.1 DUF1643 domain-containing protein -
  I6G41_RS13730 (I6G41_13730) - 2739616..2739819 (+) 204 WP_115352741.1 hypothetical protein -
  I6G41_RS13735 (I6G41_13735) - 2739869..2742991 (-) 3123 WP_197910909.1 type I restriction endonuclease subunit R -
  I6G41_RS13740 (I6G41_13740) - 2742975..2744243 (-) 1269 WP_115352739.1 restriction endonuclease subunit S -
  I6G41_RS13745 (I6G41_13745) - 2744233..2745747 (-) 1515 WP_115352738.1 type I restriction-modification system subunit M -
  I6G41_RS13750 (I6G41_13750) - 2745787..2746263 (-) 477 WP_113342718.1 Pycsar system effector family protein -
  I6G41_RS13755 (I6G41_13755) - 2746269..2747537 (-) 1269 WP_113342709.1 adenylate/guanylate cyclase domain-containing protein -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62307.28 Da        Isoelectric Point: 9.8102

>NTDB_id=513350 I6G41_RS13710 WP_197910908.1 2736025..2737653(+) (ccrB) [Staphylococcus equorum strain FDAARGOS_884]
MQQLKQKRVGIYVRVSTEMQSAEGYSIDGQINQIKEYCNFHHFEVKDIYADRGISGKSMNRPELQRMLKDANEGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRRIANALNYKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDHPVIANGKHSPIISQELWDKVQARKKQVSKKPQVHGKGTNILTGLISCPKCSASMSASTTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVVERVNKGKQVDIAALNHDIAYKQQQFD
EVHAKLDNLIKTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQQIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=513350 I6G41_RS13710 WP_197910908.1 2736025..2737653(+) (ccrB) [Staphylococcus equorum strain FDAARGOS_884]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTCCGCGTATCAACAGAAATGCAAAGTGCAGAGGGTTATAGTAT
CGACGGTCAAATCAATCAAATCAAAGAATATTGTAACTTCCATCATTTCGAAGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGAAAGTCTATGAACCGCCCTGAGCTCCAACGTATGTTGAAGGATGCGAATGAAGGTCATATCGATTGTGTCATG
GTGTATAAAACAAACCGACTTGCACGTAATACATCAGACTTGCTCAAAATTGTCGAGGATTTGCATAAACAGAACGTCGA
ATTTTTCAGTTTGTCTGAACGTATGGAAGTCAACACTTCTTCGGGTAAACTCATGTTACAAATACTCGCAAGCTTCTCTG
AATTCGAACGCAATAACATTGTAGAAAATGTCTTCATGGGTCAAACCAGACGTGCACAAGAAGGCTATTATCAAGGGAAT
TTACCACTAGGATATGATAAAATACCTGATAGTAAGCATGAACTCATGATAAACCAACATGAAGCCAATATTGTAAAATA
TATATTTGAGTCATATGCTAAAGGCCATGGATATCGTAGAATTGCCAATGCTCTCAACTATAAAGGTTATGTCACTAAAA
AAGGTAAACCATTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTTGCCAAA
TACAAAGATTGGAATGAAAAACGTCGTAAGGGATTGAATGATCATCCGGTAATTGCTAATGGAAAGCACTCCCCTATCAT
TAGTCAAGAGCTGTGGGATAAAGTACAAGCTCGTAAGAAGCAAGTCAGCAAAAAACCACAAGTCCATGGTAAAGGGACAA
ATATTTTAACTGGGTTAATTTCGTGTCCAAAATGTTCTGCTTCTATGTCTGCGAGCACGACAACCAATACACTTAAAGAT
GGTACAAAAAAGCGAATACGCTATTATTCCTGTAGTAATTTTCGCAACAAAGGATCGAAAGTGTGTTCTGCAAATAGTGT
AAGGGCAGATGTCATAGAAAAATATGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAGGTCATCAACCAAGTCG
TAGAACGTGTCAATAAAGGGAAACAAGTCGATATAGCTGCACTTAACCATGATATCGCTTATAAGCAACAACAATTTGAT
GAAGTCCATGCGAAACTAGACAACTTGATTAAAACAATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAGCACCAACAAAATCAAGAGAAACCAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACAAATATTTCAAAACATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(302-356)

Recombinase (Recombinase)

(180-280)

Resolvase, N terminal domain (Resolvase)

(11-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

85.978

100

0.86