Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6G42_RS03915 Genome accession   NZ_CP065707
Coordinates   787567..788256 (+) Length   229 a.a.
NCBI ID   WP_038804114.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_885     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 782567..793256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G42_RS03890 (I6G42_03890) gpsB 782606..782935 (+) 330 WP_038804118.1 cell division regulator GpsB -
  I6G42_RS03900 (I6G42_03900) - 783422..784579 (+) 1158 WP_038804117.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  I6G42_RS03905 (I6G42_03905) mapZ 784592..786055 (+) 1464 WP_038804116.1 cell division site-positioning protein MapZ -
  I6G42_RS03910 (I6G42_03910) gndA 786131..787555 (+) 1425 WP_038804115.1 NADP-dependent phosphogluconate dehydrogenase -
  I6G42_RS03915 (I6G42_03915) covR 787567..788256 (+) 690 WP_038804114.1 response regulator transcription factor Regulator
  I6G42_RS03920 (I6G42_03920) - 788355..789335 (+) 981 WP_038804113.1 N-acetylmuramoyl-L-alanine amidase family protein -
  I6G42_RS03925 (I6G42_03925) mvk 789453..790331 (+) 879 WP_038804112.1 mevalonate kinase -
  I6G42_RS03930 (I6G42_03930) mvaD 790313..791266 (+) 954 WP_038804110.1 diphosphomevalonate decarboxylase -
  I6G42_RS03935 (I6G42_03935) - 791253..792260 (+) 1008 WP_038804109.1 phosphomevalonate kinase -
  I6G42_RS03940 (I6G42_03940) fni 792244..793245 (+) 1002 WP_038804108.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26713.88 Da        Isoelectric Point: 8.0259

>NTDB_id=513296 I6G42_RS03915 WP_038804114.1 787567..788256(+) (covR) [Streptococcus oralis strain FDAARGOS_885]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGGKALSMALQTDYDLILLNARLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=513296 I6G42_RS03915 WP_038804114.1 787567..788256(+) (covR) [Streptococcus oralis strain FDAARGOS_885]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGGGAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGACAAGCTGAGTCGGACAAAACCTGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACTAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGGTATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463