Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   I6G43_RS04630 Genome accession   NZ_CP065706
Coordinates   971174..972976 (+) Length   600 a.a.
NCBI ID   WP_038806176.1    Uniprot ID   A0A7T2ZMG3
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 966174..977976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS04610 (I6G43_04610) smpB 967467..967934 (+) 468 WP_038806180.1 SsrA-binding protein SmpB -
  I6G43_RS04615 (I6G43_04615) tehB 967949..968809 (+) 861 WP_038806179.1 SAM-dependent methyltransferase TehB -
  I6G43_RS04620 (I6G43_04620) - 968974..970122 (+) 1149 WP_038806178.1 DUF1887 family protein -
  I6G43_RS04625 (I6G43_04625) coiA 970199..971155 (+) 957 WP_038806177.1 competence protein CoiA Machinery gene
  I6G43_RS04630 (I6G43_04630) pepF 971174..972976 (+) 1803 WP_038806176.1 oligoendopeptidase F Regulator
  I6G43_RS04635 (I6G43_04635) - 972978..973691 (+) 714 WP_068981984.1 O-methyltransferase -
  I6G43_RS04640 (I6G43_04640) prsA 973757..974698 (+) 942 WP_038806175.1 peptidylprolyl isomerase PrsA -
  I6G43_RS04645 (I6G43_04645) ftsW 974888..976111 (+) 1224 WP_038806174.1 cell division peptidoglycan polymerase FtsW -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69811.72 Da        Isoelectric Point: 4.5813

>NTDB_id=513222 I6G43_RS04630 WP_038806176.1 971174..972976(+) (pepF) [Streptococcus oralis strain FDAARGOS_886]
MVLQRHEINEKDTWDLSTIYPTDQAWEEALKDLTEKVQTAAQYEGHLLDSADSLLEITEFSLDLERQVEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLEQAFSFYEPEFMEISEEQYEAFLEAQPKLQVYKHFFDKLLQKKDHVLSQREEELLAGA
GEIFGAASETFAILDNADISFPYVLDDEGNEVQLSHGTYIRLMESKNREVRRGAYEALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALSANFVPESVYDNLVAAVRKHLPLLHRYLKLRSKILGISDLKMYDVYTPLSSVEYSFTYEEALK
KAEEALAVLGDDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGGQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=513222 I6G43_RS04630 WP_038806176.1 971174..972976(+) (pepF) [Streptococcus oralis strain FDAARGOS_886]
ATGGTATTACAACGACATGAAATAAATGAAAAAGATACATGGGATCTTTCGACTATCTACCCAACAGATCAGGCTTGGGA
AGAAGCCTTGAAAGATTTAACTGAAAAAGTACAAACAGCAGCCCAGTATGAGGGGCATCTCTTGGACAGCGCAGACAGTT
TGCTTGAGATCACAGAATTCTCACTTGACTTGGAACGCCAAGTTGAAAAGCTTTATGTCTACGCGCATATGAAAAATGAC
CAGGACACGCGTGAAGCCAAGTATCAAGAGTACTATGCTAAGGCAATGACCCTATACAGTCAGTTAGAACAAGCCTTTTC
ATTCTATGAACCTGAGTTTATGGAGATTAGCGAAGAGCAGTATGAGGCCTTCCTAGAAGCTCAACCAAAACTCCAAGTTT
ACAAACACTTTTTTGACAAGCTCTTGCAAAAGAAAGACCACGTTCTTTCGCAACGTGAGGAAGAATTACTTGCTGGAGCA
GGAGAAATCTTTGGTGCTGCTAGTGAAACCTTCGCTATTTTGGACAATGCGGATATTAGCTTCCCATACGTGCTTGATGA
CGAAGGCAATGAAGTGCAACTCTCACACGGTACTTACATCCGTTTGATGGAGTCTAAAAACCGTGAAGTGCGTCGTGGTG
CCTATGAAGCCCTTTATGCGACATATGAGCAATTCCAACACACTTATGCTAAGACCTTGCAGACAAATGTTAAGGTGCAA
AACTACCGAGCAAAAGTTCGCAACTATAAGAGTGCTCGCCATGCAGCCCTCTCAGCAAACTTTGTTCCAGAAAGTGTCTA
TGACAATCTAGTAGCGGCAGTTCGCAAGCATTTGCCACTCTTGCATCGTTACCTTAAACTTCGTTCTAAAATCTTGGGGA
TTTCTGATCTCAAGATGTACGATGTCTACACTCCACTGTCTTCAGTAGAATACAGCTTTACTTATGAGGAAGCCTTGAAA
AAGGCAGAAGAGGCCTTGGCAGTCTTGGGTGACGACTACTTGAGCCGTGTCAAACGTGCCTTTAGTGAGCGTTGGATTGA
TGTCTATGAAAACCAAGGCAAGCGTTCTGGTGCCTACTCTGGTGGTTCTTATGATACCAATGCCTTTATGCTTCTCAACT
GGCAGGACAATCTAGACAATCTCTTTACCCTTGTCCATGAGACTGGTCACAGTATGCATTCAAGCTATACTCGTGAAACT
CAGCCTTATGTTTACGGAGATTACTCTATCTTCTTGGCAGAGATTGCCTCAACGACCAACGAAAATATCTTGACGGAGAA
ATTATTGGAGGAAGTGGAAGACGATGCAACTCGTTTTGCTATTCTTAACAACTTCTTGGACGGTTTCCGTGGAACGGTCT
TCCGTCAAACTCAATTCGCTGAGTTCGAACATGCTATCCACCAAGCAGATCAAAATGGAGAAGTCTTGACAAGTGATTTC
CTCAATAAACTCTACGCTGACTTGAACCAAGAGTACTATGGACTCAGCAAAGAAGACAATCCTGAAATCCAGTACGAATG
GGCACGCATTCCTCACTTCTACTATAACTACTATGTGTATCAGTATTCAACAGGTTTTGCAGCTGCTTCAGCCTTGGCTG
AGAAGATTGTCCATGGTGGTCAGGAAGATCGTGACCGTTATATCGACTACCTCAAGGCTGGTAAGTCTGACTATCCGCTT
AATGTCATGAGAAAAGCAGGAGTGGATATGGAGAAGGAAGACTATCTCAACGATGCTTTTGCAGTCTTTGAACGCCGTTT
GAATGAGTTTGAAGCCCTTGTTGAAAAATTGGGACTGGCTTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T2ZMG3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.282

99.333

0.668