Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6G43_RS02375 Genome accession   NZ_CP065706
Coordinates   503138..503827 (+) Length   229 a.a.
NCBI ID   WP_000517999.1    Uniprot ID   A0A7T2ZPD5
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 498138..508827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS02350 (I6G43_02350) gpsB 498192..498521 (+) 330 WP_000146526.1 cell division regulator GpsB -
  I6G43_RS02360 (I6G43_02360) - 499007..500164 (+) 1158 WP_000659722.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  I6G43_RS02365 (I6G43_02365) mapZ 500177..501625 (+) 1449 WP_038806401.1 cell division site-positioning protein MapZ -
  I6G43_RS02370 (I6G43_02370) gndA 501702..503126 (+) 1425 WP_000158790.1 NADP-dependent phosphogluconate dehydrogenase -
  I6G43_RS02375 (I6G43_02375) covR 503138..503827 (+) 690 WP_000517999.1 DNA-binding response regulator Regulator
  I6G43_RS02380 (I6G43_02380) cbpF 503926..504948 (+) 1023 WP_038806400.1 choline-binding protein CbpF -
  I6G43_RS02385 (I6G43_02385) mvk 505068..505946 (+) 879 WP_000163330.1 mevalonate kinase -
  I6G43_RS02390 (I6G43_02390) mvaD 505928..506881 (+) 954 WP_000375371.1 diphosphomevalonate decarboxylase -
  I6G43_RS02395 (I6G43_02395) - 506868..507875 (+) 1008 WP_000562385.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26839.06 Da        Isoelectric Point: 8.0271

>NTDB_id=513209 I6G43_RS02375 WP_000517999.1 503138..503827(+) (covR) [Streptococcus oralis strain FDAARGOS_886]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQIDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=513209 I6G43_RS02375 WP_000517999.1 503138..503827(+) (covR) [Streptococcus oralis strain FDAARGOS_886]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTTGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGATAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCTCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCAGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAGGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGGTATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T2ZPD5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467