Detailed information NTG0512262

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: KUU70_RS18035
• Genome accession: NZ_CP077977
• Coordinates: 3845468..3846748 (-)
• Length: 426 a.a.
• NCBI ID: WP_003087924.1
• Uniprot ID: Q02KU5
• Organism: Pseudomonas aeruginosa strain ZPPH29
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3840468..3851748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KUU70_RS18025 (KUU70_18020)	hupB	3842532..3842804 (-)	273	WP_003087931.1	nucleoid-associated protein HU-beta	-
KUU70_RS18030 (KUU70_18025)	lon	3842940..3845336 (-)	2397	WP_003087926.1	endopeptidase La	-
KUU70_RS18035 (KUU70_18030)	clpX	3845468..3846748 (-)	1281	WP_003087924.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
KUU70_RS18040 (KUU70_18035)	clpP	3846853..3847494 (-)	642	WP_023115406.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
KUU70_RS18045 (KUU70_18040)	tig	3847588..3848898 (-)	1311	WP_003087920.1	trigger factor	-
KUU70_RS18050 (KUU70_18045)	parR	3849130..3849837 (+)	708	WP_003098126.1	response regulator transcription factor ParR	-
KUU70_RS18055 (KUU70_18050)	parS	3849838..3851124 (+)	1287	WP_023085103.1	sensor histidine kinase ParS	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46991.78 Da
• Isoelectric Point: 4.8347

>NTDB_id=512262 KUU70_RS18035 WP_003087924.1 3845468..3846748(-) (clpX) [Pseudomonas aeruginosa strain ZPPH29]
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSGHKLPAPKEIRTILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKDDIELGKSNILMIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TRNILFICGGAFAGLERVIQNRSARGGIGFNAEVRSQEMGKKVGEAFKEVEPEDLVKFGLIPEFVGRLPVIATLDELDEA
ALMQILTEPKNALTKQYAKLFEMEGVDLEFRPDALKAVARKALERKTGARGLRSILEGILLDTMYEIPSQQDVSKVVIDE
SVIDGSSQPLMIYENSEKPAKAAPEA

Nucleotide

• Length: 1281 bp

>NTDB_id=512262 KUU70_RS18035 WP_003087924.1 3845468..3846748(-) (clpX) [Pseudomonas aeruginosa strain ZPPH29]
ATGACTGATACCCGCAACGGCGAGGACAACGGCAAGCTGCTGTATTGCTCCTTCTGCGGCAAGAGCCAGCACGAAGTGCG
CAAGTTGATTGCCGGCCCCTCGGTCTTTATCTGCGACGAGTGTGTCGACCTGTGCAATGACATCATCCGCGAGGAGGTGC
AGGAAGCGCAGGCGGAAAGTAGTGGGCACAAACTTCCGGCGCCGAAAGAGATCCGCACCATCCTCGATCAGTACGTGATC
GGGCAGGAGCGGGCCAAGAAGGTTCTGGCGGTAGCGGTATACAACCACTACAAGCGCCTCAACCAGCGTGACAAGAAGGA
CGATATCGAGCTCGGCAAGAGCAACATTCTGATGATCGGCCCAACCGGCTCGGGCAAGACCCTGCTGGCCGAGACCCTCG
CACGTCTGCTGAACGTGCCGTTCACCATCGCCGATGCGACCACGCTGACGGAAGCGGGCTACGTGGGCGAGGATGTCGAG
AACATCATCCAGAAGCTCTTGCAGAAGTGCGATTACGATGTGGAGAAGGCCCAGATGGGCATCGTCTACATCGACGAGAT
CGACAAGATCTCCCGGAAATCGGACAACCCCTCCATCACTCGCGACGTTTCCGGCGAGGGTGTGCAGCAGGCCCTGCTGA
AGCTCATCGAGGGCACCGTTGCCTCGGTACCGCCGCAGGGCGGTCGCAAGCATCCGCAGCAGGAGTTCCTGCAGGTCGAT
ACGCGCAACATCCTGTTCATCTGCGGCGGCGCTTTCGCCGGTCTGGAGCGGGTCATCCAGAACCGTTCCGCGCGCGGCGG
CATCGGTTTCAATGCCGAAGTGCGCAGTCAGGAGATGGGCAAGAAGGTCGGCGAGGCGTTCAAGGAAGTCGAACCGGAAG
ATCTCGTCAAGTTCGGTCTTATTCCCGAATTTGTAGGGCGTTTGCCGGTGATCGCGACTCTTGATGAGCTCGACGAGGCT
GCGCTCATGCAGATCCTGACCGAGCCGAAGAACGCTCTCACCAAGCAGTACGCCAAGCTGTTCGAAATGGAAGGCGTCGA
TCTCGAATTCCGTCCGGACGCACTCAAGGCGGTTGCCCGCAAGGCGCTCGAACGCAAGACCGGTGCACGTGGCTTGCGTT
CAATTCTCGAAGGTATCCTTCTCGATACCATGTACGAGATTCCCTCCCAGCAGGATGTCAGCAAGGTGGTCATCGATGAG
AGTGTCATCGATGGCTCGTCGCAACCCCTGATGATCTACGAGAACAGCGAAAAGCCAGCCAAGGCTGCGCCTGAGGCATG
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (113-311)

3D structure

• AlphaFold DB: Q02KU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	60.934	95.54	0.582
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.198	94.836	0.523