Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   IQE12_RS03225 Genome accession   NZ_CP065515
Coordinates   658080..658649 (+) Length   189 a.a.
NCBI ID   WP_181188043.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GDY8P96A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 653080..663649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IQE12_RS03200 (IQE12_03200) cysE 654293..654940 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  IQE12_RS03205 (IQE12_03205) cysS 654924..656324 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  IQE12_RS03210 (IQE12_03210) - 656317..656721 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  IQE12_RS03215 (IQE12_03215) rlmB 656729..657475 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  IQE12_RS03220 (IQE12_03220) - 657475..657999 (+) 525 WP_000664738.1 NYN domain-containing protein -
  IQE12_RS03225 (IQE12_03225) sigH 658080..658649 (+) 570 WP_181188043.1 sigma-70 family RNA polymerase sigma factor Regulator
  IQE12_RS03230 (IQE12_03230) rpmG 658764..658907 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  IQE12_RS03235 (IQE12_03235) secE 658963..659145 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  IQE12_RS03240 (IQE12_03240) nusG 659158..659706 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  IQE12_RS03245 (IQE12_03245) rplK 659887..660309 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  IQE12_RS03250 (IQE12_03250) rplA 660517..661209 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  IQE12_RS03255 (IQE12_03255) rplJ 661481..661981 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  IQE12_RS03260 (IQE12_03260) rplL 662024..662392 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  IQE12_RS03265 (IQE12_03265) - 662567..663175 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23125.07 Da        Isoelectric Point: 9.7681

>NTDB_id=511536 IQE12_RS03225 WP_181188043.1 658080..658649(+) (sigH) [Staphylococcus aureus strain GDY8P96A]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPRKI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=511536 IQE12_RS03225 WP_181188043.1 658080..658649(+) (sigH) [Staphylococcus aureus strain GDY8P96A]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAAAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

99.471

100

0.995
  sigH Staphylococcus aureus N315

97.354

100

0.974