Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   SIR_RS15030 Genome accession   NC_022246
Coordinates   1077928..1079736 (-) Length   602 a.a.
NCBI ID   WP_041787470.1    Uniprot ID   -
Organism   Streptococcus intermedius B196     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1072928..1084736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS15005 (SIR_1036) - 1073881..1074333 (-) 453 WP_021002882.1 MarR family transcriptional regulator -
  SIR_RS15010 (SIR_1037) - 1074436..1075020 (-) 585 WP_009568384.1 uracil-DNA glycosylase family protein -
  SIR_RS15020 (SIR_1038) pepV 1075785..1077185 (-) 1401 WP_021002883.1 dipeptidase PepV -
  SIR_RS15025 (SIR_1039) - 1077214..1077819 (-) 606 WP_021002884.1 nitroreductase family protein -
  SIR_RS15030 (SIR_1040) uvrC 1077928..1079736 (-) 1809 WP_041787470.1 excinuclease ABC subunit UvrC Machinery gene
  SIR_RS15035 (SIR_1041) ptsP 1080116..1081849 (-) 1734 WP_021002886.1 phosphoenolpyruvate--protein phosphotransferase -
  SIR_RS15040 (SIR_1042) - 1081851..1082114 (-) 264 WP_003068444.1 phosphocarrier protein HPr -
  SIR_RS15045 (SIR_1043) nrdH 1082497..1082715 (+) 219 WP_021002887.1 glutaredoxin-like protein NrdH -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69321.97 Da        Isoelectric Point: 9.4027

>NTDB_id=51110 SIR_RS15030 WP_041787470.1 1077928..1079736(-) (uvrC) [Streptococcus intermedius B196]
MNNLIKSKLELLPTGPGCYIHKNKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEVEDFEFIVTESNIEALLLEIN
LIKENQPKYNIMLKDDKSYPFIKITNEIYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPEKVCF
YYHIGQCRAHTICHNDLHFFQEMAQEVADFLKGHDNKIIDELKGKMTSAAEKMEFEKAAEYRDLLQSIATLRTKQRVMAR
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNMFPYYNDPDEDFLTYIGQFYQNKSHLVPNEILIPSDIDEESVRAV
VDTKILKPQRGEKKQLVNLAIKNAQVSLQQKFDLLEKSIEKTQGAIENLGRLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FINGKPSKKDYRKYKIKTVIGPDDYASMREVIKRRYSRVIRDGLLPPDLIVIDGGQGQVNIAKDVIQHQLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMKHFKSL
TKIKEASVEEIVEVGVPRKVAEAVQGKLRRAIDKKEIIPDTF

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=51110 SIR_RS15030 WP_041787470.1 1077928..1079736(-) (uvrC) [Streptococcus intermedius B196]
ATGAACAACTTAATTAAATCAAAATTAGAGTTATTGCCAACTGGTCCAGGATGTTATATCCACAAGAATAAAAATGGTAC
GATCATCTATGTGGGAAAAGCCAAGAATTTGCGCAATCGGGTGCGTTCGTATTTTCGCGGAAGTCATGATACTAAAACGG
AAGCGTTAGTGTCTGAGGTTGAGGATTTTGAGTTTATTGTCACTGAGTCTAATATTGAAGCCTTGTTGCTTGAAATCAAT
CTGATCAAGGAAAATCAGCCCAAATACAACATCATGCTTAAGGACGATAAGTCCTACCCTTTTATCAAAATCACCAATGA
GATATATCCGCGACTTATTATTACACGTCAGGTTAAGAAAGATGGTGGTTTATATTTTGGTCCGTATCCTGATGTAGGTG
CTGCGAACGAAATTAAGCGCCTGCTGGATCGCATTTTTCCTTTCCGTAAGTGTACCAATCCACCTGAGAAAGTTTGCTTC
TACTATCATATCGGACAGTGTCGAGCTCATACTATCTGCCATAATGATCTACATTTCTTTCAAGAGATGGCTCAAGAAGT
AGCAGATTTCCTCAAAGGTCATGATAATAAGATTATTGATGAATTGAAAGGAAAAATGACTAGTGCTGCTGAAAAGATGG
AATTTGAAAAAGCGGCTGAATACCGAGATTTGCTTCAAAGTATTGCGACACTTCGCACCAAGCAACGAGTGATGGCAAGG
GATTTACAGAATCGGGATGTCTTTGGCTATTATGTGGACAAAGGATGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAAGG
AAAACTCATTGAGCGAGATGTAAATATGTTTCCTTATTACAATGACCCTGACGAGGATTTTTTGACTTATATTGGACAAT
TTTATCAGAATAAATCTCATCTGGTGCCCAATGAAATTTTGATTCCATCTGATATTGACGAGGAATCAGTACGGGCTGTG
GTGGATACAAAAATCCTTAAGCCTCAACGAGGAGAAAAGAAACAGCTGGTCAATCTGGCAATTAAGAATGCTCAAGTTAG
TTTACAGCAGAAGTTTGACTTATTAGAGAAATCTATTGAAAAAACGCAAGGAGCAATTGAAAATCTAGGCCGGCTCCTCA
ATATTCCCACTCCAGTTCGGATTGAGTCGTTTGATAATTCCAATATTATGGGAACAAGTCCTGTTTCAGCTATGGTGGTC
TTTATCAATGGCAAACCCAGCAAAAAAGATTATCGCAAGTATAAGATTAAGACAGTTATCGGTCCGGATGACTATGCGAG
TATGCGAGAAGTGATTAAGCGCCGTTATAGCCGAGTCATACGAGATGGTTTACTACCGCCTGATCTGATTGTCATTGATG
GTGGTCAGGGACAAGTAAACATTGCAAAAGACGTCATTCAACATCAATTAGGTTTAGATATTCCTATCGCTGGTTTGCAA
AAGAACGACAAGCATCAGACTCATGAATTGCTTTTTGGTGATCCGTTGGAAGTGGTCGAATTATCTCGCAATTCACAGGA
ATTTTTCCTTTTGCAACGCATTCAAGATGAAGTCCACCGCTTTGCCATTACCTTCCATCGCCAGCTCCGGTCTAAGAATT
CCTTCTCATCACAACTAGATGGCATTGAAGGACTGGGGCCTAAACGCAAGCAAAATCTCATGAAACATTTCAAATCGCTA
ACTAAGATTAAAGAAGCAAGTGTTGAGGAAATTGTCGAAGTAGGCGTACCGCGAAAAGTGGCAGAGGCTGTTCAGGGGAA
GTTAAGAAGGGCTATAGATAAAAAAGAAATAATACCCGATACATTTTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(538-585)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(197-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

89.796

97.674

0.877
  uvrC Streptococcus pneumoniae R6

89.456

97.674

0.874
  uvrC Streptococcus pneumoniae D39

89.456

97.674

0.874

Multiple sequence alignment