Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SPAF_RS01295 Genome accession   NC_017905
Coordinates   243485..244783 (+) Length   432 a.a.
NCBI ID   WP_041826192.1    Uniprot ID   -
Organism   Streptococcus parasanguinis FW213     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 238485..249783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPAF_RS01270 (Spaf_0234) - 239247..239879 (+) 633 WP_014712738.1 response regulator transcription factor -
  SPAF_RS01275 (Spaf_0235) - 239924..241324 (+) 1401 WP_013904767.1 Cof-type HAD-IIB family hydrolase -
  SPAF_RS01280 (Spaf_0236) - 241326..241691 (+) 366 WP_003018098.1 S1 RNA-binding domain-containing protein -
  SPAF_RS01285 (Spaf_0237) cysK 241741..242664 (-) 924 WP_003004014.1 cysteine synthase A -
  SPAF_RS01290 (Spaf_0238) - 242788..243429 (-) 642 WP_041826515.1 YigZ family protein -
  SPAF_RS01295 (Spaf_0239) comFA/cflA 243485..244783 (+) 1299 WP_041826192.1 DEAD/DEAH box helicase Machinery gene
  SPAF_RS01300 (Spaf_0240) - 244780..245445 (+) 666 WP_014712742.1 ComF family protein -
  SPAF_RS01305 (Spaf_0241) raiA 245527..246069 (+) 543 WP_003012610.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49399.34 Da        Isoelectric Point: 9.2710

>NTDB_id=51100 SPAF_RS01295 WP_041826192.1 243485..244783(+) (comFA/cflA) [Streptococcus parasanguinis FW213]
MKIEDSYGRLLTESQMTNDLKEIAQELPTIEKQNGRYQCFRCGSMIDQKLWKLSEEVLYCRACIQLGRIRSDQKLYAIAQ
HDFEGQEVLNWKGTLTSYQQEVSDGLIQAVKEGGNALVHAVTGAGKTEMMYQVVATAIKSGQAVCIATPRIDVCIELYGR
MKDDFSCPISLLHGKSEPYFRTPLVIATTHQLLKFFQAFDLLIIDEVDAFPYVDNSILYKAAQNAIKKGGNTLYLTATST
DELDKKVKKKEIIRYSLPRRFHGNPLVVPEIKWVPKIREKIEKGRIPYELLQLIKKQRQTHYPLLIFVSEIELGQQFTEN
LKKYFPKETVGFVSSQTTDRLRMVEEFRNRAITMLVSTTILERGVTFPFVDVFVLESNHKLFTKSALVQISGRVGRSKER
PTGKLLFLSDGITREMKKAIKEIKEMNQEAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=51100 SPAF_RS01295 WP_041826192.1 243485..244783(+) (comFA/cflA) [Streptococcus parasanguinis FW213]
ATGAAGATAGAAGATTCTTATGGAAGGCTCTTAACAGAGAGTCAAATGACAAATGATCTAAAAGAAATTGCCCAAGAACT
TCCTACTATAGAAAAACAAAATGGAAGGTACCAATGTTTTCGATGTGGCAGTATGATTGATCAAAAACTTTGGAAGTTGA
GTGAAGAGGTACTGTATTGTAGAGCCTGTATCCAATTGGGAAGAATCCGGAGTGATCAAAAACTTTATGCTATTGCACAG
CATGACTTTGAAGGACAGGAGGTGTTAAACTGGAAAGGAACCTTGACTTCCTATCAACAAGAGGTATCCGATGGTCTCAT
CCAAGCAGTTAAGGAAGGGGGAAATGCCTTGGTACATGCTGTGACAGGAGCTGGGAAAACGGAAATGATGTACCAGGTTG
TAGCAACAGCAATCAAGAGTGGACAAGCAGTCTGTATTGCTACCCCAAGAATCGATGTCTGTATCGAACTGTACGGAAGG
ATGAAGGACGATTTTTCCTGCCCCATCTCTTTGCTTCATGGGAAATCGGAACCCTATTTTAGAACGCCTTTGGTAATCGC
AACAACCCACCAATTGCTAAAATTTTTTCAGGCCTTTGATCTCCTTATTATAGATGAGGTAGATGCTTTTCCCTATGTGG
ACAATTCAATCTTATATAAAGCAGCTCAGAATGCGATAAAAAAAGGGGGGAATACGCTATATTTAACAGCAACCTCTACA
GATGAGTTAGATAAAAAGGTCAAGAAAAAAGAAATCATTCGTTATAGCCTTCCAAGACGATTCCATGGGAACCCACTAGT
GGTCCCTGAAATAAAATGGGTGCCGAAAATTAGGGAAAAAATAGAAAAAGGAAGAATCCCTTACGAACTATTGCAACTGA
TCAAGAAACAAAGACAGACTCACTACCCATTGTTAATCTTTGTATCTGAAATAGAATTAGGACAACAATTTACTGAGAAC
TTAAAAAAATACTTTCCCAAAGAAACAGTAGGTTTTGTATCCTCACAGACAACAGACCGCCTACGAATGGTAGAAGAGTT
TAGAAACAGAGCCATAACCATGCTAGTCTCGACAACAATTTTAGAAAGAGGAGTGACCTTTCCGTTTGTAGATGTCTTTG
TTTTAGAAAGTAATCACAAATTATTTACTAAAAGTGCACTCGTACAAATTTCAGGAAGGGTCGGTCGAAGTAAAGAAAGA
CCAACAGGTAAACTACTTTTTCTATCAGATGGCATAACACGAGAAATGAAAAAAGCGATCAAAGAAATAAAGGAAATGAA
TCAGGAGGCTGGATTTTGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(290-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

59.122

100

0.593
  comFA/cflA Streptococcus pneumoniae Rx1

58.891

100

0.59
  comFA/cflA Streptococcus pneumoniae D39

58.891

100

0.59
  comFA/cflA Streptococcus pneumoniae R6

58.891

100

0.59
  comFA/cflA Streptococcus mitis NCTC 12261

58.891

100

0.59
  comFA/cflA Streptococcus pneumoniae TIGR4

58.661

100

0.588
  comFA Lactococcus lactis subsp. cremoris KW2

50

92.13

0.461
  comFA Latilactobacillus sakei subsp. sakei 23K

37.413

100

0.375

Multiple sequence alignment