Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   ST4021_RS08850 Genome accession   NZ_CP065493
Coordinates   1714857..1715813 (-) Length   318 a.a.
NCBI ID   WP_011681684.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4021     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1709857..1720813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4021_RS08815 (ST4021_08845) proC 1710417..1711187 (+) 771 WP_011226616.1 pyrroline-5-carboxylate reductase -
  ST4021_RS08820 (ST4021_08850) - 1711217..1711879 (-) 663 WP_011681679.1 type II CAAX endopeptidase family protein -
  ST4021_RS08825 (ST4021_08855) - 1711976..1712419 (-) 444 WP_011681680.1 hypothetical protein -
  ST4021_RS08830 - 1712493..1712831 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  ST4021_RS08835 - 1712875..1713150 (-) 276 WP_011681681.1 hypothetical protein -
  ST4021_RS08840 (ST4021_08865) - 1713162..1713359 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  ST4021_RS08845 (ST4021_08870) - 1713608..1714801 (-) 1194 WP_014608740.1 acetate kinase -
  ST4021_RS08850 (ST4021_08875) comYH 1714857..1715813 (-) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  ST4021_RS08855 (ST4021_08880) comGG 1715858..1716175 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG -
  ST4021_RS08860 (ST4021_08885) comYF 1716153..1716590 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  ST4021_RS08865 (ST4021_08890) comGE 1716574..1716867 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  ST4021_RS08870 (ST4021_08895) comYD 1716839..1717267 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  ST4021_RS08875 (ST4021_08900) comYC 1717227..1717553 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  ST4021_RS08880 (ST4021_08905) comYB 1717550..1718650 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  ST4021_RS08885 (ST4021_08910) comYA 1718532..1719473 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  ST4021_RS08890 (ST4021_08915) - 1719554..1719916 (-) 363 WP_023909982.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35843.02 Da        Isoelectric Point: 4.7891

>NTDB_id=510983 ST4021_RS08850 WP_011681684.1 1714857..1715813(-) (comYH) [Streptococcus thermophilus strain 4021]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANELIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTQEKQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIAEVVNSV
AVYIQGDAVRPHILKESNVIISDLPIGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAIFLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTKNAPETFVYPLSDLKNPRVLKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=510983 ST4021_RS08850 WP_011681684.1 1714857..1715813(-) (comYH) [Streptococcus thermophilus strain 4021]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACTATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTTGCTAATGAGCTCATCATCAAAAACAATG
AGAAATTACGGGCGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTTTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATCGGATTTATCATTCTGTACTTGCTCGAAGGTTTGACCCA
GGAAAAACAATTAGATATCTTGGAGATTGGTTCGGGAACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGGATGGAAGTTGATGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGAGGTGGTGAATTCAGTA
GCGGTTTATATCCAAGGGGATGCTGTTCGACCACATATTCTCAAAGAGAGCAACGTTATTATCAGCGATTTACCTATAGG
TTACTACCCTAATGATGAGATTGCGAGTCGTTTCAAGGTGGCAGCAACTGGCGAACACACTTATGCCCATCATCTTCTTA
TGGAGCAATCGCTTAAGTATTTGAAGAAAGATGGTATTGCTATTTTTTTGGCACCAACCAATCTTTTGACAAGCCCTCAA
AGTGATCTGCTTAAGAAGTGGTTATCAGGATATGCTGATATTATTGCTGTTATTACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTAAAAAAACAAACTAAAAATGCTCCTGAGACCTTCGTTTACCCACTTAGCG
ATTTGAAAAATCCAAGGGTCCTCAAGGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

68.889

99.057

0.682
  comYH Streptococcus mutans UA140

68.889

99.057

0.682