Detailed information NTG0510955

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ST4021_RS03285
• Genome accession: NZ_CP065493
• Coordinates: 615015..616016 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain 4021
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 610015..621016

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4021_RS03265 (ST4021_03255)	smpB	611118..611582 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
ST4021_RS03270 (ST4021_03260)	-	611736..613142 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
ST4021_RS03275 (ST4021_03265)	-	613144..613509 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
ST4021_RS03280 (ST4021_03270)	-	613612..614697 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
ST4021_RS03285 (ST4021_03275)	ccpA	615015..616016 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
ST4021_RS03290 (ST4021_03280)	-	616075..616272 (+)	198	WP_014608125.1	hypothetical protein	-
ST4021_RS03295	-	616378..616602 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
ST4021_RS03300 (ST4021_03285)	-	616603..617142 (+)	540	WP_011680936.1	hypothetical protein	-
ST4021_RS03305 (ST4021_03290)	-	617155..618270 (+)	1116	WP_011680937.1	glycerate kinase	-
ST4021_RS03310 (ST4021_03295)	-	618317..618772 (-)	456	WP_011680938.1	YueI family protein	-
ST4021_RS03315 (ST4021_03300)	eno	618981..620285 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=510955 ST4021_RS03285 WP_004197422.1 615015..616016(+) (ccpA) [Streptococcus thermophilus strain 4021]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=510955 ST4021_RS03285 WP_004197422.1 615015..616016(+) (ccpA) [Streptococcus thermophilus strain 4021]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547