Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   SIR_RS12170 Genome accession   NC_022246
Coordinates   463198..466878 (+) Length   1226 a.a.
NCBI ID   WP_021002530.1    Uniprot ID   T1ZEH1
Organism   Streptococcus intermedius B196     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 458198..471878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS12160 (SIR_0476) - 458593..459807 (+) 1215 WP_021002528.1 ABC transporter permease -
  SIR_RS12165 (SIR_0477) rexB 459929..463201 (+) 3273 WP_021002529.1 ATP-dependent nuclease subunit B Machinery gene
  SIR_RS12170 (SIR_0478) rexA 463198..466878 (+) 3681 WP_021002530.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  SIR_RS12175 (SIR_0479) glgB 467392..469302 (+) 1911 WP_009569031.1 1,4-alpha-glucan branching protein GlgB -
  SIR_RS12180 (SIR_0480) - 469306..470448 (+) 1143 WP_021002531.1 glucose-1-phosphate adenylyltransferase -
  SIR_RS12185 (SIR_0481) glgD 470438..471577 (+) 1140 WP_021002532.1 glucose-1-phosphate adenylyltransferase subunit GlgD -

Sequence

Protein


Download         Length: 1226 a.a.        Molecular weight: 141378.31 Da        Isoelectric Point: 6.2547

>NTDB_id=51086 SIR_RS12170 WP_021002530.1 463198..466878(+) (rexA) [Streptococcus intermedius B196]
MKRLPFLNQAEICALQHQEAQSNKTQKRTAEQIEAIYSSGQNILVSASAGSGKTFVMVQRIIDQIMRGVRIEQLFISTFT
VKAASELKERLEKELSKALKETTNEELKQHLAQQLADIPNADIGTMDSFTQKVLNKYGYLLELAPNFRILQSASEQLLLQ
NEVFEQVFEDFYQSDQAALFKKMVKNFTGQRKDLYGFREQVYKIYSFLQSTSNPIEWLEKDFLKGYEFADFQEEKAQLLT
KTKEALFDLEDFFRYHLIHEAKEFPKAKYLENVQRVLDGLASLQGPSSEKVYLTALNHIVEISRASNGKALTNSGRKEEL
KEIINAYNEKRKEKIQVLRDLANQFYRFEFQMTYHEEAKEILLVLQQFMKSFVTSYLNRKKEENAFEFADISHFAIQILE
ECSDVRQFYRNKYHEVMVDEYQDTNHTQERMLELLSNGDNRFMVGDIKQSIYRFRQADPQIFNEKFKTYKEDSRQGKLIV
LKENFRSHLEVLEATNDVFKRLMDEEVGEIDYNETHYLVAGNPDKKEPNPLYQTEFLIYDGALEADKEENDKEVSSVSAG
EVELVIKEIIRLYNEENVQFEDITLLTASRTRNDVILAEFAKYGIPVVSDGGEDNYLQSVEVMVVLDTLRTINNPLNDYA
LVALLKSPMFNFTEDELARLALQKKVTEANYVAHQENLYEKLKNARNGYGQYPELITPPLLKKIQQFQGTLQAWREYAKT
NSLYDLLWKIYQDRFYYDYVGALPNGAGRQANLYALTLRANDYEKMSFKGLSRFIGMIDKILETQNDLASVVSAAPKHAV
RLMTVHKSKGLEFKYVFLLNMDKVFNRKDSSSALILSRQNGVGIKYVADVAVDVADKLAPNHVRLSIDTLPYEQNEREIH
LASISEQMRLLYVAMTRAERKLYLVGKGHQNSLEKRSFPTPVKGHLAASIRQSMTSFQDWMWALHVVFEKDNLAFSTRFV
TDNDLTSEKIGQLKLKDAVIEEDLIDNRQSEDIRRALDILENVDRLNTQYRAAIHLPSVQTPSQIKKFYEPVIDTDGVEI
MEKRNPTIVGKASFELPNFAKKAPVTGAQIGSAVHELMQRIPLDQAPTIAVLRKVLKQVQAEASVKKKIDLQKIASFFGT
ELGQLLLKYADRVYREAPFAMLKQDPASGQDFVVRGILDGYLLLADRIILFDYKTDQYTHSSELVKRYRGQLALYAEALR
RSYGIEKIEKYLVLLGESQLQVVKVD

Nucleotide


Download         Length: 3681 bp        

>NTDB_id=51086 SIR_RS12170 WP_021002530.1 463198..466878(+) (rexA) [Streptococcus intermedius B196]
ATGAAGAGACTACCATTTTTGAATCAAGCAGAAATTTGTGCTTTGCAGCATCAAGAAGCACAGTCTAATAAAACTCAAAA
ACGTACAGCAGAGCAAATCGAAGCCATCTACTCCTCTGGTCAAAACATTCTTGTGTCTGCTTCTGCAGGATCAGGAAAAA
CCTTTGTAATGGTGCAGCGGATTATTGATCAAATTATGCGGGGAGTTCGTATTGAGCAGCTCTTCATTTCAACTTTCACC
GTCAAAGCAGCTAGTGAATTAAAAGAGCGCTTGGAGAAAGAGTTGTCCAAGGCCTTGAAAGAAACAACTAATGAGGAACT
TAAACAGCACTTGGCGCAGCAATTAGCTGATATTCCCAATGCAGATATTGGAACTATGGACTCTTTCACTCAAAAAGTCC
TAAATAAATATGGTTATCTGTTGGAGTTGGCACCAAATTTTCGCATTTTACAAAGTGCGAGTGAACAATTATTGCTACAA
AACGAAGTTTTTGAGCAAGTTTTTGAAGACTTCTATCAATCTGATCAGGCAGCTTTGTTTAAAAAAATGGTCAAAAACTT
TACAGGTCAGAGGAAAGATTTGTATGGTTTCCGAGAGCAGGTTTATAAGATTTATTCTTTTTTGCAGTCTACTAGTAATC
CAATAGAATGGTTGGAAAAAGACTTTTTGAAAGGCTATGAGTTTGCAGATTTCCAAGAAGAGAAAGCACAACTCTTAACG
AAGACTAAAGAAGCCCTCTTTGATTTAGAAGATTTTTTCCGTTATCATTTGATCCATGAAGCCAAGGAATTTCCCAAAGC
AAAATATCTTGAAAATGTGCAGCGTGTGCTTGATGGGCTTGCAAGTTTACAAGGGCCTTCCTCTGAGAAAGTCTATCTCA
CAGCGCTCAATCATATTGTAGAAATATCGCGTGCCAGCAATGGAAAAGCCTTGACGAACAGCGGTCGTAAAGAAGAATTA
AAAGAAATCATCAACGCCTATAACGAAAAACGCAAAGAAAAAATTCAAGTTCTACGAGACTTGGCGAATCAATTTTATCG
TTTTGAATTTCAAATGACTTACCATGAGGAAGCAAAAGAAATTTTACTTGTTTTGCAGCAATTTATGAAATCGTTTGTTA
CAAGCTATTTGAATCGCAAAAAAGAAGAAAATGCTTTTGAATTTGCGGACATTAGTCATTTTGCTATTCAGATTTTAGAA
GAATGTTCGGATGTGCGTCAGTTTTATAGAAACAAATACCATGAAGTTATGGTAGATGAATATCAAGATACTAACCACAC
GCAAGAGCGGATGCTAGAACTGTTATCAAATGGGGATAATCGCTTTATGGTGGGGGATATTAAACAGTCTATTTACCGTT
TTCGTCAAGCGGATCCGCAGATTTTCAATGAGAAATTCAAAACCTATAAAGAAGATAGCAGACAAGGGAAATTGATTGTC
TTAAAAGAGAATTTTCGCAGTCATTTGGAAGTTTTGGAAGCCACCAATGATGTGTTTAAGCGCCTCATGGATGAGGAAGT
GGGAGAAATTGATTACAATGAAACGCATTATCTGGTAGCTGGAAATCCTGATAAAAAAGAACCAAATCCCTTGTATCAGA
CAGAATTTCTCATTTATGATGGAGCGCTTGAAGCGGATAAGGAGGAGAATGACAAGGAGGTTTCTTCTGTTTCTGCAGGA
GAAGTAGAACTGGTAATTAAAGAAATTATTCGCCTGTACAATGAAGAAAATGTCCAATTTGAGGATATTACTTTGCTAAC
GGCTTCGCGGACGCGCAACGATGTGATTTTAGCTGAATTTGCTAAATATGGTATTCCTGTCGTTTCAGACGGTGGTGAGG
ACAATTACCTTCAGTCTGTTGAAGTCATGGTGGTGTTAGACACCTTGCGTACAATTAACAACCCTCTCAATGATTATGCT
TTGGTGGCGCTTTTAAAATCGCCAATGTTCAACTTTACAGAAGATGAATTGGCACGTTTAGCTTTGCAAAAGAAGGTGAC
TGAGGCAAATTATGTTGCCCATCAGGAAAATCTCTATGAGAAGTTGAAGAATGCTCGGAATGGGTACGGGCAATATCCTG
AACTTATCACGCCTCCTCTTTTAAAAAAAATCCAGCAATTTCAAGGAACACTACAGGCTTGGCGAGAGTATGCAAAAACA
AATTCACTATATGATTTGCTTTGGAAAATTTATCAAGATCGCTTTTATTACGATTATGTGGGAGCTTTACCAAATGGAGC
GGGACGTCAGGCCAATCTTTATGCACTGACCTTACGAGCAAATGATTACGAAAAAATGAGTTTTAAAGGCTTGTCACGTT
TTATTGGGATGATTGATAAAATCTTGGAAACACAGAATGATTTAGCCAGTGTAGTCAGTGCAGCTCCGAAACATGCGGTT
CGCCTGATGACGGTTCATAAGAGCAAAGGTTTGGAATTTAAATATGTCTTTTTGCTCAATATGGACAAAGTATTTAATCG
TAAAGATAGCAGTTCTGCTTTGATTCTCAGTCGTCAAAATGGTGTTGGAATCAAGTATGTGGCTGATGTTGCAGTAGATG
TTGCTGATAAGTTAGCTCCAAACCATGTTCGTTTGTCTATTGATACTCTGCCCTATGAGCAAAATGAACGTGAGATCCAT
TTAGCCAGCATTTCGGAACAAATGCGTCTACTCTATGTCGCCATGACACGCGCTGAAAGGAAACTGTATTTAGTTGGTAA
AGGTCATCAGAATAGTTTGGAGAAAAGAAGCTTCCCTACTCCAGTGAAGGGGCATTTAGCTGCATCTATCAGGCAAAGTA
TGACAAGTTTTCAAGATTGGATGTGGGCTTTACATGTAGTATTTGAGAAAGATAATTTAGCTTTTTCAACGCGATTTGTG
ACAGATAATGACTTGACAAGTGAAAAAATAGGTCAACTGAAATTGAAAGATGCGGTTATTGAAGAGGATTTAATAGACAA
TCGCCAATCTGAGGATATTCGCAGGGCTTTGGATATTTTGGAAAATGTAGATCGACTGAATACTCAGTATCGAGCTGCCA
TTCATCTACCGAGTGTTCAAACACCAAGCCAAATCAAGAAATTTTATGAACCAGTTATAGATACAGATGGCGTTGAAATT
ATGGAGAAAAGGAATCCGACCATTGTAGGAAAAGCTTCTTTTGAGCTACCAAATTTTGCTAAAAAAGCTCCAGTTACAGG
AGCGCAAATTGGTAGCGCTGTCCATGAACTGATGCAGCGTATTCCTTTGGATCAAGCCCCTACGATAGCTGTTTTGAGAA
AAGTTTTAAAACAGGTTCAGGCAGAAGCAAGTGTTAAAAAGAAAATTGATTTGCAAAAGATAGCTAGTTTCTTTGGGACT
GAACTTGGACAGCTCCTTTTGAAGTATGCAGACAGAGTATATCGTGAAGCCCCTTTTGCTATGTTAAAGCAGGATCCAGC
AAGTGGACAAGATTTTGTTGTTCGTGGGATATTAGATGGCTATCTTCTATTAGCTGACCGAATTATTCTCTTTGACTATA
AAACGGATCAATACACTCATTCAAGTGAATTAGTCAAACGATACCGAGGGCAATTAGCACTTTATGCCGAAGCTCTTAGG
CGTTCATATGGTATTGAAAAAATTGAAAAATACCTAGTGCTACTAGGTGAATCTCAACTTCAAGTAGTCAAGGTGGATTA
G

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1068-1204)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(29-469)

UvrD-like helicase C-terminal domain (UvrD_C)

(479-904)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZEH1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

60.163

99.918

0.601

Multiple sequence alignment