Detailed information
Bioinformatically predicted
Overview
| Name | amiE | Type | Regulator |
| Locus tag | ST90730_RS06645 | Genome accession | NZ_CP065481 |
| Coordinates | 1277200..1278285 (-) | Length | 361 a.a. |
| NCBI ID | WP_011226304.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain 90730 | ||
| Function | internalize XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1260744..1332517 | 1277200..1278285 | within | 0 |
Gene organization within MGE regions
Location: 1260744..1332517
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ST90730_RS06565 (ST90730_06590) | liaF | 1260752..1261450 (-) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
| ST90730_RS06570 | - | 1261716..1261871 (-) | 156 | WP_011226290.1 | ion channel | - |
| ST90730_RS06575 (ST90730_06600) | stkP/pknB | 1262508..1264379 (-) | 1872 | WP_011226292.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| ST90730_RS06580 (ST90730_06605) | - | 1264379..1265116 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| ST90730_RS06585 (ST90730_06610) | rsmB | 1265160..1266482 (-) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| ST90730_RS06590 (ST90730_06615) | fmt | 1266472..1267407 (-) | 936 | WP_002951411.1 | methionyl-tRNA formyltransferase | - |
| ST90730_RS06595 (ST90730_06620) | - | 1267425..1269821 (-) | 2397 | WP_011227404.1 | primosomal protein N' | - |
| ST90730_RS06600 (ST90730_06625) | rpoZ | 1269963..1270277 (-) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| ST90730_RS06605 (ST90730_06630) | gmk | 1270299..1270928 (-) | 630 | WP_011226296.1 | guanylate kinase | - |
| ST90730_RS06610 (ST90730_06635) | ftsY | 1271161..1272552 (-) | 1392 | WP_011226297.1 | signal recognition particle-docking protein FtsY | - |
| ST90730_RS06615 (ST90730_06640) | - | 1272566..1273381 (-) | 816 | WP_156703494.1 | Cof-type HAD-IIB family hydrolase | - |
| ST90730_RS06620 (ST90730_06645) | - | 1273374..1274168 (-) | 795 | WP_059257398.1 | HAD family hydrolase | - |
| ST90730_RS06625 (ST90730_06650) | - | 1274351..1274728 (+) | 378 | WP_011226300.1 | GntR family transcriptional regulator | - |
| ST90730_RS06630 (ST90730_06655) | - | 1274733..1275431 (+) | 699 | WP_011226301.1 | ABC transporter ATP-binding protein | - |
| ST90730_RS06635 (ST90730_06660) | - | 1275443..1276228 (+) | 786 | WP_002951425.1 | hypothetical protein | - |
| ST90730_RS06640 (ST90730_06665) | amiF | 1276278..1277207 (-) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| ST90730_RS06645 (ST90730_06670) | amiE | 1277200..1278285 (-) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| ST90730_RS06650 (ST90730_06675) | amiD | 1278295..1279221 (-) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| ST90730_RS06655 (ST90730_06680) | amiC | 1279221..1280714 (-) | 1494 | WP_011227407.1 | ABC transporter permease | Regulator |
| ST90730_RS06660 (ST90730_06685) | amiA | 1280776..1282743 (-) | 1968 | WP_059257397.1 | peptide ABC transporter substrate-binding protein | Regulator |
| ST90730_RS06665 (ST90730_06690) | - | 1283099..1284509 (+) | 1411 | Protein_1258 | ISL3 family transposase | - |
| ST90730_RS06670 (ST90730_06695) | amiA3 | 1284393..1286360 (-) | 1968 | WP_011227411.1 | peptide ABC transporter substrate-binding protein | Regulator |
| ST90730_RS06675 (ST90730_06700) | - | 1286564..1286754 (-) | 191 | Protein_1260 | IS3 family transposase | - |
| ST90730_RS06680 | - | 1286748..1287149 (-) | 402 | Protein_1261 | ABC transporter ATP-binding protein | - |
| ST90730_RS06685 (ST90730_06715) | - | 1287144..1287504 (-) | 361 | Protein_1262 | TatD family hydrolase | - |
| ST90730_RS06690 (ST90730_06720) | - | 1287853..1289058 (+) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| ST90730_RS06695 (ST90730_06725) | - | 1289104..1290456 (-) | 1353 | Protein_1264 | IS3 family transposase | - |
| ST90730_RS06700 (ST90730_06730) | pta | 1290542..1291525 (-) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| ST90730_RS06705 (ST90730_06735) | - | 1291539..1292435 (-) | 897 | WP_011226316.1 | RluA family pseudouridine synthase | - |
| ST90730_RS06710 (ST90730_06740) | - | 1292432..1293268 (-) | 837 | WP_041827075.1 | NAD kinase | - |
| ST90730_RS06715 (ST90730_06745) | - | 1293240..1293914 (-) | 675 | WP_002951443.1 | GTP pyrophosphokinase family protein | - |
| ST90730_RS06720 (ST90730_06750) | - | 1294010..1294585 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| ST90730_RS06725 (ST90730_06755) | - | 1294948..1295919 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| ST90730_RS06730 (ST90730_06760) | - | 1295923..1297035 (+) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| ST90730_RS06735 (ST90730_06765) | - | 1297037..1297384 (+) | 348 | WP_002948028.1 | DUF1831 domain-containing protein | - |
| ST90730_RS06740 (ST90730_06770) | - | 1297528..1298187 (+) | 660 | WP_041827076.1 | redox-sensing transcriptional repressor Rex | - |
| ST90730_RS06745 (ST90730_06775) | - | 1298180..1298875 (+) | 696 | WP_011227423.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| ST90730_RS06750 (ST90730_06780) | radC | 1298928..1299614 (-) | 687 | WP_011227424.1 | DNA repair protein RadC | - |
| ST90730_RS06755 (ST90730_06785) | - | 1299793..1301133 (-) | 1341 | WP_231108743.1 | DUF2142 domain-containing protein | - |
| ST90730_RS06760 (ST90730_06790) | - | 1301282..1303027 (-) | 1746 | WP_011227426.1 | rhamnan synthesis F family protein | - |
| ST90730_RS06765 (ST90730_06795) | - | 1303029..1304729 (-) | 1701 | WP_041827077.1 | glycosyltransferase family 4 protein | - |
| ST90730_RS06770 (ST90730_06800) | - | 1304747..1305949 (-) | 1203 | WP_059257395.1 | ABC transporter ATP-binding protein | - |
| ST90730_RS06775 (ST90730_06805) | - | 1305949..1306755 (-) | 807 | WP_011227429.1 | ABC transporter permease | - |
| ST90730_RS06780 (ST90730_06810) | - | 1306755..1307696 (-) | 942 | WP_011227430.1 | glycosyltransferase family 2 protein | - |
| ST90730_RS06785 (ST90730_06815) | - | 1307693..1308841 (-) | 1149 | WP_011227431.1 | glycosyltransferase family 1 protein | - |
| ST90730_RS06790 (ST90730_06820) | - | 1308960..1309742 (-) | 783 | WP_011227432.1 | glycosyltransferase family A protein | - |
| ST90730_RS06795 (ST90730_06825) | - | 1309743..1310075 (-) | 333 | WP_011227433.1 | DUF2304 domain-containing protein | - |
| ST90730_RS06800 (ST90730_06830) | - | 1310081..1310770 (-) | 690 | WP_011227434.1 | glycosyltransferase family 2 protein | - |
| ST90730_RS06805 (ST90730_06835) | - | 1310872..1311332 (-) | 461 | Protein_1286 | glycosyltransferase family 2 protein | - |
| ST90730_RS06810 (ST90730_06840) | - | 1311397..1312383 (-) | 987 | WP_011227437.1 | glycosyltransferase family 2 protein | - |
| ST90730_RS06815 (ST90730_06845) | - | 1312380..1313639 (-) | 1260 | WP_011227438.1 | lipopolysaccharide biosynthesis protein | - |
| ST90730_RS06820 (ST90730_06850) | rfbD | 1313760..1314611 (-) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| ST90730_RS06825 (ST90730_06855) | - | 1314729..1315655 (-) | 927 | WP_011227439.1 | glycosyltransferase family 2 protein | - |
| ST90730_RS06830 (ST90730_06860) | - | 1315665..1316000 (-) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| ST90730_RS06835 (ST90730_06865) | rpoD | 1316054..1317163 (-) | 1110 | WP_011227440.1 | RNA polymerase sigma factor RpoD | - |
| ST90730_RS06840 (ST90730_06870) | dnaG | 1317167..1318978 (-) | 1812 | WP_011227441.1 | DNA primase | - |
| ST90730_RS06845 (ST90730_06875) | rpsU | 1319350..1319526 (-) | 177 | WP_011226340.1 | 30S ribosomal protein S21 | - |
| ST90730_RS06850 (ST90730_06880) | - | 1319907..1320860 (+) | 954 | WP_041826943.1 | IS30 family transposase | - |
| ST90730_RS06855 (ST90730_06885) | - | 1320966..1321760 (-) | 795 | WP_011227442.1 | ABC transporter substrate-binding protein | - |
| ST90730_RS06860 (ST90730_06890) | - | 1321853..1322962 (-) | 1110 | WP_041828295.1 | aminotransferase | - |
| ST90730_RS06865 (ST90730_06895) | - | 1323309..1324106 (-) | 798 | WP_059257394.1 | transporter substrate-binding domain-containing protein | - |
| ST90730_RS06870 (ST90730_06900) | - | 1324103..1324933 (-) | 831 | WP_041828297.1 | transporter substrate-binding domain-containing protein | - |
| ST90730_RS06875 (ST90730_06905) | - | 1325147..1325611 (-) | 465 | WP_011226345.1 | 8-oxo-dGTP diphosphatase | - |
| ST90730_RS06880 (ST90730_06910) | uvrB | 1325656..1327647 (-) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| ST90730_RS06885 | - | 1327794..1328039 (-) | 246 | WP_231779859.1 | hypothetical protein | - |
| ST90730_RS06890 (ST90730_06920) | - | 1328334..1329270 (-) | 937 | Protein_1303 | type II CAAX endopeptidase family protein | - |
| ST90730_RS06895 (ST90730_06925) | - | 1329469..1331679 (+) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| ST90730_RS06900 (ST90730_06930) | - | 1331679..1332419 (+) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 361 a.a. Molecular weight: 39864.62 Da Isoelectric Point: 4.7435
>NTDB_id=510255 ST90730_RS06645 WP_011226304.1 1277200..1278285(-) (amiE) [Streptococcus thermophilus strain 90730]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA
Nucleotide
Download Length: 1086 bp
>NTDB_id=510255 ST90730_RS06645 WP_011226304.1 1277200..1278285(-) (amiE) [Streptococcus thermophilus strain 90730]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiE | Streptococcus thermophilus LMG 18311 |
100 |
100 |
1 |
| amiE | Streptococcus thermophilus LMD-9 |
100 |
100 |
1 |
| amiE | Streptococcus salivarius strain HSISS4 |
96.953 |
100 |
0.97 |
| oppD | Streptococcus mutans UA159 |
54.441 |
96.676 |
0.526 |