Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ST90729_RS01895 Genome accession   NZ_CP065480
Coordinates   345104..346423 (+) Length   439 a.a.
NCBI ID   WP_347116692.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90729     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 340104..351423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90729_RS01870 (ST90729_01870) - 340960..341724 (+) 765 WP_002947187.1 ABC transporter ATP-binding protein -
  ST90729_RS01875 (ST90729_01875) - 341724..342434 (+) 711 WP_002947183.1 ABC transporter ATP-binding protein -
  ST90729_RS01880 (ST90729_01880) - 342570..343228 (+) 659 Protein_318 CBS domain-containing protein -
  ST90729_RS01885 (ST90729_01885) cysK 343395..344321 (-) 927 WP_014607992.1 cysteine synthase A -
  ST90729_RS01890 (ST90729_01890) - 344423..345049 (-) 627 WP_002949745.1 YigZ family protein -
  ST90729_RS01895 (ST90729_01895) comFA/cflA 345104..346423 (+) 1320 WP_347116692.1 DEAD/DEAH box helicase Machinery gene
  ST90729_RS01900 (ST90729_01900) - 346404..347066 (+) 663 WP_002949747.1 ComF family protein -
  ST90729_RS01905 (ST90729_01905) raiA 347145..347693 (+) 549 WP_022096635.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50658.74 Da        Isoelectric Point: 9.5663

>NTDB_id=510175 ST90729_RS01895 WP_347116692.1 345104..346423(+) (comFA/cflA) [Streptococcus thermophilus strain 90729]
MIPKEYYGRLFTKEQLPVDYLSEAVKLESMIKVDKKLRCKRCYSRIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWSGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEMIYNIVAYVLENKNRVVIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIVDEVDAFPFVGNVMLNHTVKQAKTETGRYIYLTATST
LALEEQVRLGAIEKHHLASRFHGNPLVLPRFFWQGRLQKSLTSEKLPRPLIHQIKKQRKSNFPLLIFFPNIALGEKFSIT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFPQVDVFVCMANHYLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCREEINAMNKKGGFENEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=510175 ST90729_RS01895 WP_347116692.1 345104..346423(+) (comFA/cflA) [Streptococcus thermophilus strain 90729]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTACCAGTGGATTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCGAATAGAGGAAGATTGGCAATTACCAA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGAAAAGAACTCTATTACTTTCCCTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTCAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGCAAGACAGAGATGATTTATAATATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGTCATCGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGC
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTGTTGACGAAGTTGATGCCTTTCCATTTGTAG
GGAATGTCATGTTAAATCATACTGTTAAACAGGCAAAGACGGAAACAGGCCGGTATATTTACTTAACAGCAACTTCTACA
TTAGCTTTAGAAGAGCAAGTGCGCCTTGGAGCTATAGAAAAGCATCACCTTGCTAGTCGTTTCCACGGAAATCCTTTAGT
CCTTCCTCGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAGCGAGAAGCTTCCAAGGCCTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTCCCCAATATAGCATTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATATCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATTGTTGAGAAATT
CCGAAAAAAAGAATTGTCAATCTTAGTGACGACAACTATTCTCGAACGTGGTGTTACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATTACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGGAAGAAATAAATGCAATGAA
TAAAAAAGGAGGGTTTGAAAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-193)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae D39

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae R6

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae TIGR4

54.756

98.178

0.538
  comFA/cflA Streptococcus mitis NCTC 12261

54.419

97.95

0.533
  comFA/cflA Streptococcus mitis SK321

53.488

97.95

0.524
  comFA Lactococcus lactis subsp. cremoris KW2

45.476

95.672

0.435
  comFA Latilactobacillus sakei subsp. sakei 23K

36.782

99.089

0.364