Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ST90729_RS01655 Genome accession   NZ_CP065480
Coordinates   300645..302162 (+) Length   505 a.a.
NCBI ID   WP_173940561.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90729     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 295645..307162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90729_RS01625 - 295925..296095 (+) 171 Protein_267 ascorbate 6-phosphate lactonase -
  ST90729_RS01630 (ST90729_01635) - 296112..296783 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  ST90729_RS01635 (ST90729_01640) - 296823..298187 (-) 1365 WP_014727321.1 potassium transporter TrkG -
  ST90729_RS01640 (ST90729_01645) rsmG 298257..298970 (-) 714 WP_138496718.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ST90729_RS01645 (ST90729_01650) - 299267..299803 (+) 537 WP_002946488.1 YceD family protein -
  ST90729_RS01650 (ST90729_01655) covR 299959..300648 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  ST90729_RS01655 (ST90729_01660) covS 300645..302162 (+) 1518 WP_173940561.1 HAMP domain-containing histidine kinase Regulator
  ST90729_RS01660 (ST90729_01665) nrdR 302284..302763 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  ST90729_RS01665 (ST90729_01670) - 302760..303935 (+) 1176 WP_347116689.1 DnaD domain protein -
  ST90729_RS01670 (ST90729_01675) dnaI 303939..304841 (+) 903 WP_002946786.1 primosomal protein DnaI -
  ST90729_RS01675 (ST90729_01680) der 304947..306257 (+) 1311 WP_232973523.1 ribosome biogenesis GTPase Der -
  ST90729_RS01680 (ST90729_01685) - 306321..306990 (+) 670 Protein_278 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57550.91 Da        Isoelectric Point: 5.1731

>NTDB_id=510173 ST90729_RS01655 WP_173940561.1 300645..302162(+) (covS) [Streptococcus thermophilus strain 90729]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKAIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGDLALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=510173 ST90729_RS01655 WP_173940561.1 300645..302162(+) (covS) [Streptococcus thermophilus strain 90729]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAGCTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGGCCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGATTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(39-187)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.622

99.406

0.941